CDMOs Play a Critical Role in the Biopharmaceutical Ecosystem.
CDMO
biologics
bioprocess
foundry
monoclonal antibody
semiconductor
Journal
Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
Titre abrégé: Front Bioeng Biotechnol
Pays: Switzerland
ID NLM: 101632513
Informations de publication
Date de publication:
2022
2022
Historique:
received:
22
12
2021
accepted:
07
03
2022
entrez:
7
4
2022
pubmed:
8
4
2022
medline:
8
4
2022
Statut:
epublish
Résumé
Biopharmaceutical industries have advanced significantly after the millennium. Novel biopharmaceuticals have been developed one after another, and blockbuster drugs have been produced. Accompanying the increase in the demand for biopharmaceuticals, a business model called "contract development manufacturing organization (CDMO)" has emerged. A CDMO is entrusted with the development and manufacturing of production processes from pharmaceutical companies. In this review, we identify the success factors of the biopharmaceutical CDMO by analyzing the foundry business for the semiconductor industry. Furthermore, we also review monoclonal antibody production platforms and new technologies that are critical aspects of differentiation strategies in the biopharmaceutical CDMO.
Identifiants
pubmed: 35387299
doi: 10.3389/fbioe.2022.841420
pii: 841420
pmc: PMC8978586
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
841420Informations de copyright
Copyright © 2022 Kurata, Ishino, Ohshima and Yohda.
Déclaration de conflit d'intérêts
HK, TI and YO were employed by the company AGC Inc. TI was employed by the copmany AGC Biologics. The remaining author declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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