Multisensory stimulation decreases phantom limb distortions and is optimally integrated.
Behavioral neuroscience
Bioelectronics
Clinical neuroscience
Techniques in neuroscience
Journal
iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038
Informations de publication
Date de publication:
15 Apr 2022
15 Apr 2022
Historique:
received:
13
05
2021
revised:
16
10
2021
accepted:
17
03
2022
entrez:
8
4
2022
pubmed:
9
4
2022
medline:
9
4
2022
Statut:
epublish
Résumé
The multisensory integration of signals from different senses is crucial to develop an unambiguous percept of the environment and our body. Losing a limb causes drastic changes in the body, sometimes causing pain and distorted phantom limb perception. Despite the debate over why these phenomena arise, some researchers suggested that they might be linked to an impairment of multisensory signals inflow and integration. Therefore, reestablishing optimally integrated sensory feedback could be crucial. The related benefits on sensory performance and body self-representation are still to be demonstrated, particularly in lower-limb amputees. We present a multisensory framework combining Virtual reality and electro-cutaneous stimulation that allows the optimal integration of visuo-tactile stimuli in lower-limb amputees even if nonspatially matching. We also showed that this multisensory stimulation allowed faster sensory processing, higher embodiment, and reductions in phantom limb distortions. Our findings support the development of multisensory rehabilitation approaches, restoring a correct body representation.
Identifiants
pubmed: 35391829
doi: 10.1016/j.isci.2022.104129
pii: S2589-0042(22)00399-6
pmc: PMC8980810
doi:
Types de publication
Journal Article
Langues
eng
Pagination
104129Informations de copyright
© 2022 The Authors.
Déclaration de conflit d'intérêts
S.R. holds shares of Sensars Neuroprosthetics Sarl, a company working to commercialize novel solutions for leg amputees. Other authors do not have anything to declare.
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