Primary herpes simplex virus type 1 infection with acute liver failure in solid organ transplantation: Report of three cases and review.

Donor derived transmitted disease HSV-1 Herpes simplex virus hepatitis SOT Transplantation

Journal

IDCases
ISSN: 2214-2509
Titre abrégé: IDCases
Pays: Netherlands
ID NLM: 101634540

Informations de publication

Date de publication:
2022
Historique:
received: 12 11 2021
revised: 31 01 2022
accepted: 23 03 2022
entrez: 8 4 2022
pubmed: 9 4 2022
medline: 9 4 2022
Statut: epublish

Résumé

Herpes virus infections is not uncommon in solid organ transplantation patients. We report 3 cases with primary Herpes simplex virus type-1 (HSV1) infection with acute liver failure (ALF). This is a rare and potentially fatal entity that could be a donor-derived infection. Although the initial clinical presentation is non-specific, it should be considered as a differential diagnosis in HSV-negative serology patients with liver failure and empirical treatment must be started in combination with a drastic reduction of immunosuppression. A strategy of HSV prophylaxis for pre-transplant HSV seronegative patients must be stablished in order to reduce the risk of clinical disease.

Identifiants

pubmed: 35392601
doi: 10.1016/j.idcr.2022.e01485
pii: S2214-2509(22)00113-5
pmc: PMC8980616
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e01485

Informations de copyright

© 2022 Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

The authors don’t have conflicts of interest, on the publication of this paper.

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Auteurs

Carolt Arana (C)

Nephrology Service, Hospital Clínic-IDIBAPS, Barcelona, Spain.

Frederic Cofan (F)

Nephrology Service, Hospital Clínic-IDIBAPS, Barcelona, Spain.

Pablo Ruiz (P)

Liver Unit, Hospital Clínic, IDIBAPS, CIBERehd, Barcelona, Spain.

Evelyn Hermida (E)

Nephrology Service, Hospital Clínic-IDIBAPS, Barcelona, Spain.

Javier Fernández (J)

Liver Unit, Hospital Clínic, IDIBAPS, CIBERehd, Barcelona, Spain.

Jordi Colmenero (J)

Liver Unit, Hospital Clínic, IDIBAPS, CIBERehd, Barcelona, Spain.

Xavier Forns (X)

Liver Unit, Hospital Clínic, IDIBAPS, CIBERehd, Barcelona, Spain.

Laia Escude (L)

Liver Unit, Hospital Clínic, IDIBAPS, CIBERehd, Barcelona, Spain.

David Cucchiari (D)

Nephrology Service, Hospital Clínic-IDIBAPS, Barcelona, Spain.

Asunción Moreno (A)

Infectious Diseases Service, Hospital Clínic, IDIBAPS, Barcelona, Spain.

Marta Bodro (M)

Infectious Diseases Service, Hospital Clínic, IDIBAPS, Barcelona, Spain.

Sabina Herrera (S)

Infectious Diseases Service, Hospital Clínic, IDIBAPS, Barcelona, Spain.

Camino Rodriguez (C)

Transplant Coordination Service, Hospital Clínic, Barcelona, Spain.

David Paredes (D)

Transplant Coordination Service, Hospital Clínic, Barcelona, Spain.

Fritz Diekmann (F)

Nephrology Service, Hospital Clínic-IDIBAPS, Barcelona, Spain.

Classifications MeSH