Short-term and residential exposure to air pollution: Associations with inflammatory biomarker levels in adults living in northern France.


Journal

The Science of the total environment
ISSN: 1879-1026
Titre abrégé: Sci Total Environ
Pays: Netherlands
ID NLM: 0330500

Informations de publication

Date de publication:
10 Aug 2022
Historique:
received: 04 10 2021
revised: 24 03 2022
accepted: 29 03 2022
pubmed: 11 4 2022
medline: 7 6 2022
entrez: 10 4 2022
Statut: ppublish

Résumé

Air pollution has an impact on health, and low-grade inflammation might be one of the underlying mechanisms. The objective of the present study of adults from northern France was to assess the associations between short-term and residential exposure to air pollution and levels of various inflammatory biomarkers. The cross-sectional Enquête Littoral Souffle Air Biologie Environnement (ELISABET) study was conducted from 2011 to 2013 in the Lille and Dunkirk urban areas of northern France. Here, we evaluated the associations between PM We assessed 3074 participants for the association with hsCRP and a subsample of 982 non-smokers from Lille for the association with plasma cytokine levels. A 10 μg/m Short-term exposure to air pollution was associated with higher serum hsCRP levels in adult residents of two urban areas in northern France. Our results suggest that along with other factors, low-grade inflammation might explain the harmful effects of air pollution on health.

Identifiants

pubmed: 35398417
pii: S0048-9697(22)02078-2
doi: 10.1016/j.scitotenv.2022.154985
pii:
doi:

Substances chimiques

Air Pollutants 0
Biomarkers 0
Cytokines 0
Particulate Matter 0
C-Reactive Protein 9007-41-4
Nitrogen Dioxide S7G510RUBH

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

154985

Informations de copyright

Copyright © 2022 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest LD, RM and JMLG have contributed to an expert report (commissioned by Lille European Metropole) entitled “Rapport d'expertise à propos de la localisation de la piscine du projet d'aménagement de la gare Saint Sauveur à Lille” [Expert report on the location of the swimming pool in the Saint Sauveur station development project in Lille] but did not receive any personal fees. Other authors declare that they have no conflicts of interest.

Auteurs

Marion Darras-Hostens (M)

Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000 Lille, France. Electronic address: marion.hostens.etu@univ-lille.fr.

Djamal Achour (D)

Univ. Lille, CHU Lille, Institut Pasteur de Lille, ULR 4483 - IMPECS - IMPact de l'Environnement Chimique sur la Santé, F-59000 Lille, France. Electronic address: djamal.achour@univ-lille.fr.

Manon Muntaner (M)

Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000 Lille, France. Electronic address: manon.muntaner@pasteur-lille.fr.

Céline Grare (C)

Univ. Lille, CHU Lille, Institut Pasteur de Lille, ULR 4483 - IMPECS - IMPact de l'Environnement Chimique sur la Santé, F-59000 Lille, France. Electronic address: celine.grare@univ-lille.fr.

Gianni Zarcone (G)

Univ. Lille, CHU Lille, Institut Pasteur de Lille, ULR 4483 - IMPECS - IMPact de l'Environnement Chimique sur la Santé, F-59000 Lille, France. Electronic address: gianni.zarcone@univ-lille.fr.

Guillaume Garçon (G)

Univ. Lille, CHU Lille, Institut Pasteur de Lille, ULR 4483 - IMPECS - IMPact de l'Environnement Chimique sur la Santé, F-59000 Lille, France. Electronic address: guillaume.garcon@univ-lille.fr.

Philippe Amouyel (P)

Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000 Lille, France. Electronic address: philippe.amouyel@univ-lille.fr.

Farid Zerimech (F)

Univ. Lille, CHU Lille, Institut Pasteur de Lille, ULR 4483 - IMPECS - IMPact de l'Environnement Chimique sur la Santé, F-59000 Lille, France. Electronic address: Farid.ZERIMECH@chu-lille.fr.

Régis Matran (R)

Univ. Lille, CHU Lille, Institut Pasteur de Lille, ULR 4483 - IMPECS - IMPact de l'Environnement Chimique sur la Santé, F-59000 Lille, France. Electronic address: regis.matran@univ-lille.fr.

Jean-Marc Lo Guidice (JL)

Univ. Lille, CHU Lille, Institut Pasteur de Lille, ULR 4483 - IMPECS - IMPact de l'Environnement Chimique sur la Santé, F-59000 Lille, France. Electronic address: jean-marc.lo-guidice@univ-lille.fr.

Luc Dauchet (L)

Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000 Lille, France. Electronic address: luc.dauchet@chru-lille.fr.

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