Repeat pancreatic resection for metachronous pancreatic metastasis from renal cell carcinoma: A case report.

Pancreatic metastasis Renal cancer Surgical resection

Journal

International journal of surgery case reports
ISSN: 2210-2612
Titre abrégé: Int J Surg Case Rep
Pays: Netherlands
ID NLM: 101529872

Informations de publication

Date de publication:
May 2022
Historique:
received: 09 02 2022
revised: 27 03 2022
accepted: 31 03 2022
pubmed: 11 4 2022
medline: 11 4 2022
entrez: 10 4 2022
Statut: ppublish

Résumé

Pancreatic metastasis (PM) from renal cell carcinoma (RCC) is relatively rare. Surgical resection of PM from RCC is considered as the first choice treatment for achieving long-term prognosis. Herein, we report a case of secondary multiple metastases from RCC to the remnant pancreas following pancreatectomy, with a review of the relevant literature. A 69-year-old man who underwent left nephrectomy for RCC (T2N0M0, stage II) 12 years ago was referred to our hospital. Multiple metastases to the pancreatic head from RCC occurred 2 years after the primary surgery, for which pancreaticoduodenectomy was performed. Nine years after metastatic resection, multiple tumors of the remnant pancreas were detected on dynamic computed tomography (CT); all tumors showed strong enhancement in the early phase, which persisted into the late phase. The tumors were round, the maximum diameter of the tumor was 20 mm, and they were hyperintense on T2-weighted magnetic resonance imaging. Positron emission tomography-CT revealed slight fluorodeoxyglucose uptake in the tumor. Multiple PMs were diagnosed, and the remnant pancreas was completely resected. Two years later, the patient was alive and showed no recurrence. Surgical resection could provide long-term prognosis, even if secondary PM from RCC occurs metachronously. Long-term follow-up is recommended after primary resection, and vigilance regarding the occurrence of PM is needed.

Sections du résumé

BACKGROUND BACKGROUND
Pancreatic metastasis (PM) from renal cell carcinoma (RCC) is relatively rare. Surgical resection of PM from RCC is considered as the first choice treatment for achieving long-term prognosis. Herein, we report a case of secondary multiple metastases from RCC to the remnant pancreas following pancreatectomy, with a review of the relevant literature.
PRESENTATION OF CASE METHODS
A 69-year-old man who underwent left nephrectomy for RCC (T2N0M0, stage II) 12 years ago was referred to our hospital. Multiple metastases to the pancreatic head from RCC occurred 2 years after the primary surgery, for which pancreaticoduodenectomy was performed. Nine years after metastatic resection, multiple tumors of the remnant pancreas were detected on dynamic computed tomography (CT); all tumors showed strong enhancement in the early phase, which persisted into the late phase. The tumors were round, the maximum diameter of the tumor was 20 mm, and they were hyperintense on T2-weighted magnetic resonance imaging. Positron emission tomography-CT revealed slight fluorodeoxyglucose uptake in the tumor. Multiple PMs were diagnosed, and the remnant pancreas was completely resected. Two years later, the patient was alive and showed no recurrence.
CONCLUSIONS CONCLUSIONS
Surgical resection could provide long-term prognosis, even if secondary PM from RCC occurs metachronously. Long-term follow-up is recommended after primary resection, and vigilance regarding the occurrence of PM is needed.

Identifiants

pubmed: 35398785
pii: S2210-2612(22)00268-1
doi: 10.1016/j.ijscr.2022.107022
pmc: PMC9006246
pii:
doi:

Types de publication

Journal Article

Langues

eng

Pagination

107022

Informations de copyright

Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.

Auteurs

Shingo Itamoto (S)

Department of Surgery, Onomichi General Hospital, Onomichi, Hiroshima, Japan. Electronic address: ittason.soccer2114@gmail.com.

Tomoyuki Abe (T)

Department of Surgery, Onomichi General Hospital, Onomichi, Hiroshima, Japan. Electronic address: t.abe.hiroshima@gmail.com.

Akihiko Oshita (A)

Department of Surgery, Onomichi General Hospital, Onomichi, Hiroshima, Japan. Electronic address: oshita-akihiko@umin.ac.jp.

Keiji Hanada (K)

Department of Gastroenterology, Onomichi General Hospital, Onomichi, Hiroshima, Japan. Electronic address: kh-ajpbd@nifty.com.

Masahiro Nakahara (M)

Department of Surgery, Onomichi General Hospital, Onomichi, Hiroshima, Japan. Electronic address: masa.samurai@go7.enjoy.ne.jp.

Toshio Noriyuki (T)

Department of Surgery, Onomichi General Hospital, Onomichi, Hiroshima, Japan. Electronic address: nori0509@hotmail.co.jp.

Classifications MeSH