The Impact of Frailty and Comorbidities on Heart Failure Outcomes.
Frailty
comorbidity
heart failure
Journal
Cardiac failure review
ISSN: 2057-7540
Titre abrégé: Card Fail Rev
Pays: England
ID NLM: 101696210
Informations de publication
Date de publication:
Jan 2022
Jan 2022
Historique:
received:
19
11
2021
accepted:
19
01
2022
entrez:
11
4
2022
pubmed:
12
4
2022
medline:
12
4
2022
Statut:
epublish
Résumé
Frailty is a multisystemic process leading to reduction of physiological reserve and a reduction in physical activity. Heart failure (HF) is recognised as a global cause of morbidity and mortality, increasing in prevalence over recent decades. Because of shared phenotypes and comorbidities, there is significant overlap and a bidirectional relationship, with frail patients being at increased risk of developing HF and vice versa. Despite this, frailty is not routinely assessed in patients with HF. Identification of these patients to direct multidisciplinary care is key, and the development of a frailty assessment tool validated in a large HF population is also an unmet need that would be of considerable benefit in directing multidisciplinary-team management. Non-pharmacological treatment should be included, as exercise and physical rehabilitation programmes offer dual benefit in frail HF patients, by treating both conditions simultaneously. The evidence for nutritional supplementation is mixed, but there is evidence that a personalised approach to nutritional support in frail HF patients can improve outcomes.
Identifiants
pubmed: 35399550
doi: 10.15420/cfr.2021.29
pmc: PMC8977991
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
e07Informations de copyright
Copyright © 2022, Radcliffe Cardiology.
Déclaration de conflit d'intérêts
Disclosure: RS reports speaker fees from Novartis, Astra Zeneca, Vyfor, Bristol-Myers Squibb, Pfizer and research grants from British Heart Foundation, NHSX and Biotronik UK, outside the submitted work. All other authors have no conflicts of interest to declare.
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