Protective Mechanism of Gandou Decoction in a Copper-Laden Hepatolenticular Degeneration Model:
cell metabolomics
copper-laden HLD hepatocyte model
gandou decoction
hepatolenticular degeneration
pharmacology
Journal
Frontiers in pharmacology
ISSN: 1663-9812
Titre abrégé: Front Pharmacol
Pays: Switzerland
ID NLM: 101548923
Informations de publication
Date de publication:
2022
2022
Historique:
received:
05
01
2022
accepted:
17
02
2022
entrez:
11
4
2022
pubmed:
12
4
2022
medline:
12
4
2022
Statut:
epublish
Résumé
Gandou decoction (GDD) is a classic prescription for the treatment of hepatolenticular degeneration (HLD) in China; however, the liver-protecting mechanism of this prescription needs further evaluation. In the present study, we explored the protective mechanisms of GDD in a copper-laden HLD model using integrated pharmacology and cellular metabolomics
Identifiants
pubmed: 35401189
doi: 10.3389/fphar.2022.848897
pii: 848897
pmc: PMC8984159
doi:
Types de publication
Journal Article
Langues
eng
Pagination
848897Informations de copyright
Copyright © 2022 Yin, Nian, Wang, Wu, Wu, Zhao, Cao, Wu and Zhou.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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