Influence of vitamin D receptor polymorphism rs2228570 on pathological scarring.

RFLP-PCR SNP VDR atrophic scar hypertrophic scar

Journal

Experimental and therapeutic medicine
ISSN: 1792-1015
Titre abrégé: Exp Ther Med
Pays: Greece
ID NLM: 101531947

Informations de publication

Date de publication:
May 2022
Historique:
received: 25 06 2021
accepted: 27 07 2021
entrez: 11 4 2022
pubmed: 12 4 2022
medline: 12 4 2022
Statut: ppublish

Résumé

The physiological process of scarring is a common denominator of interest in a plethora of medical specialties. The molecular basis whereby this process results in pathological scarring for some individuals is poorly understood at present, with clues pointing towards individual predisposition for pathological scarring. Vitamin D and its subsequent pathway plays a key role in skin metabolism and homeostasis, with alterations in the level of vitamin D receptor (VDR) seen within pathological scars. The present study investigated the role of the rs2228570 polymorphism of

Identifiants

pubmed: 35401803
doi: 10.3892/etm.2022.11264
pii: ETM-0-0-11264
pmc: PMC8987945
doi:

Types de publication

Journal Article

Langues

eng

Pagination

345

Informations de copyright

Copyright © 2020, Spandidos Publications.

Déclaration de conflit d'intérêts

The authors declare no competing interests.

Références

Int J Clin Exp Med. 2015 Dec 15;8(12):22108-16
pubmed: 26885185
J Clin Periodontol. 2006 Aug;33(8):524-8
pubmed: 16899094
Sci Rep. 2019 May 24;9(1):7829
pubmed: 31127184
Skin Res Technol. 2009 Feb;15(1):1-5
pubmed: 19152571
Burns. 2017 Nov;43(7):1506-1515
pubmed: 28778755
Acta Odontol Scand. 2019 Oct;77(7):484-494
pubmed: 30957605
Open Access Maced J Med Sci. 2019 Jan 12;7(1):65-67
pubmed: 30740162
Exp Ther Med. 2019 Aug;18(2):916-925
pubmed: 31384324

Auteurs

Roxana Flavia Ilieș (RF)

Department of Medical Genetics, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

Casian Simon Aioanei (CS)

Department of Medical Genetics, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

Salomea-Ruth Halmagyi (SR)

Department of Medical Genetics, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

Andreea Cătană (A)

Department of Medical Genetics, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Department of Oncogenetics, 'Ion Chiricuță' Oncological Institute, 400015 Cluj-Napoca, Romania.

Istvan Lukacs (I)

1st Department of Obstetrics and Gynecology, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.

Reka-Eniko Tokes (RE)

1st Department of Obstetrics and Gynecology, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.

Ioana Christina Rotar (IC)

1st Department of Obstetrics and Gynecology, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.
1st Clinic of Obstetrics and Gynecology, Emergency County Hospital, 400006 Cluj-Napoca, Romania.

Ioan Victor Pop (IV)

Department of Medical Genetics, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

Classifications MeSH