Anti-NMDAr Encephalitis and COVID-19 in a Patient With Systemic pANCA-Vasculitis and Recurrent Varicella Zoster Infection.
COVID-19
anti-NMDAr
encephalitis
varicella zoster
vasculitis
Journal
The Neurohospitalist
ISSN: 1941-8744
Titre abrégé: Neurohospitalist
Pays: United States
ID NLM: 101558199
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
entrez:
11
4
2022
pubmed:
12
4
2022
medline:
12
4
2022
Statut:
ppublish
Résumé
There is a complex interplay between systemic autoimmunity, immunosuppression, and infections. Any or all of these can result in neurologic manifestations, requiring diligence on the part of neurologists. We herein report a case of a patient on immunosuppressive treatment for a vasculitis that resulted in zoster meningoencephalitis. This was further complicated by the development of anti-NMDAr encephalitis, the etiology of which is undetermined and further discussed in this paper. The patient eventually developed COVID-19 during hospitalization, succumbing to the respiratory infection. This case emphasizes that post-infectious autoimmune disorders are becoming increasingly recognized and that they should still be considered in patients who are on immunosuppression. Practitioners should be aware of the complex relationship between autoimmunity and immunosuppression and consider both throughout the disease course.
Identifiants
pubmed: 35401915
doi: 10.1177/19418744211063709
pii: 10.1177_19418744211063709
pmc: PMC8977756
doi:
Types de publication
Case Reports
Langues
eng
Pagination
383-387Informations de copyright
© The Author(s) 2022.
Déclaration de conflit d'intérêts
Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Références
Neurol Neuroimmunol Neuroinflamm. 2018 Apr 05;5(4):e458
pubmed: 29629396
Nat Rev Gastroenterol Hepatol. 2009 Aug;6(8):444-5
pubmed: 19654597
Neurol Neuroimmunol Neuroinflamm. 2018 Jun 11;5(4):e471
pubmed: 29904645
Seizure. 2017 Oct;51:6-8
pubmed: 28750305
Neurology. 2014 Dec 9;83(24):2309-11
pubmed: 25378669
Lancet Neurol. 2016 Apr;15(4):391-404
pubmed: 26906964
Neurol Clin. 2021 Feb;39(1):197-207
pubmed: 33223083
Rheumatology (Oxford). 2020 May 1;59(Suppl 3):iii79-iii83
pubmed: 32348518
Front Neurol. 2020 Feb 18;11:38
pubmed: 32132963
J Neurol Sci. 2006 Jan 15;240(1-2):99-101
pubmed: 16274697
Ann Neurol. 2009 Jul;66(1):11-8
pubmed: 19670433
J Rheumatol. 2018 Nov;45(11):1541-1548
pubmed: 30008461
Neurotherapeutics. 2016 Jul;13(3):493-508
pubmed: 27106239
Open Med. 2013 Jun 18;7(2):e68-73
pubmed: 24348886
J Clin Virol. 2016 Oct;83:26-8
pubmed: 27529308