Two-step protocol for regeneration of immunocompetent T cells from mouse pluripotent stem cells.
Induced hematopoietic progenitor cells
Pluripotent stem cells
T cells regeneration
Transplantation
Journal
Blood science (Baltimore, Md.)
ISSN: 2543-6368
Titre abrégé: Blood Sci
Pays: United States
ID NLM: 9918248414306676
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
27
03
2020
accepted:
04
06
2020
entrez:
11
4
2022
pubmed:
25
7
2020
medline:
25
7
2020
Statut:
epublish
Résumé
Numerous efforts have been attempted to regenerate T cells in culture dish from pluripotent stem cells (PSCs). However, in vitro generated T cells exhibited extremely low activity and compromised immunocompetency in vivo. Here, we describe a two-step protocol for regenerating functional T cells using an inducible
Identifiants
pubmed: 35402823
doi: 10.1097/BS9.0000000000000049
pii: BLS-20-006
pmc: PMC8974948
doi:
Types de publication
Journal Article
Langues
eng
Pagination
79-88Commentaires et corrections
Type : ErratumIn
Informations de copyright
Copyright © 2020 The Authors. Published by Wolters Kluwer Health Inc., on behalf of the Chinese Association for Blood Sciences.
Déclaration de conflit d'intérêts
Conflicts of interest: The authors declare no conflicts of interest.
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