Horizontal transmission of disseminated neoplasia in the widespread clam Macoma balthica from the Southern Baltic Sea.
bivalve transmissible neoplasia
disease biology
infectious cancer
invertebrates
molluscs
Journal
Molecular ecology
ISSN: 1365-294X
Titre abrégé: Mol Ecol
Pays: England
ID NLM: 9214478
Informations de publication
Date de publication:
06 2022
06 2022
Historique:
revised:
24
03
2022
received:
18
01
2022
accepted:
01
04
2022
pubmed:
12
4
2022
medline:
31
5
2022
entrez:
11
4
2022
Statut:
ppublish
Résumé
Disseminated neoplasia (DN) is one of the most challenging and unrecognised diseases occurring in aquatic fauna. It has been diagnosed in four bivalve species from the Gulf of Gdańsk (Southern Baltic Sea) with the highest frequency in Macoma balthica (formerly Limecola balthica), reaching up to 94% in some populations. The aetiology of DN in the Baltic Sea has not yet been identified, with earlier studies trying to link its occurrence with environmental pollution. Taking into account recent research providing evidence that DN is horizontally transmitted as clonal cells between individuals in some bivalve species, we aimed to test whether DN is a bivalve transmissible neoplasia (BTN) in the population of M. balthica from the Gulf of Gdańsk highly affected with cancer. We examined mitochondrial cytochrome c oxidase I (mtCOI) and elongation factor 1α (EF1α) sequences of genomes obtained from haemolymph and tissues of neoplastic and healthy individuals. Sequence analysis resulted in detection of an independent transmissible cancer lineage occurring in four neoplastic clams that is not present in healthy animals. This study describes the first case of BTN in the clam M. balthica (MbaBTN), providing further insights for studies on this disease.
Identifiants
pubmed: 35403750
doi: 10.1111/mec.16464
pmc: PMC9541291
mid: NIHMS1838900
doi:
Types de publication
Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
3128-3136Subventions
Organisme : NCI NIH HHS
ID : K22 CA226047
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM007270
Pays : United States
Organisme : NHGRI NIH HHS
ID : T32 HG000035
Pays : United States
Informations de copyright
© 2022 John Wiley & Sons Ltd.
Références
Sci Rep. 2021 Dec 16;11(1):24110
pubmed: 34916573
PLoS Pathog. 2016 Oct 27;12(10):e1005904
pubmed: 27788268
Elife. 2022 Jan 18;11:
pubmed: 35040778
Bioessays. 2016 Jul;38 Suppl 1:S14-23
pubmed: 27417118
Mar Pollut Bull. 2004 Jul;49(1-2):17-22
pubmed: 15234870
Nature. 2017 Oct 11;550(7675):204-213
pubmed: 29022597
Elife. 2019 Nov 05;8:
pubmed: 31686650
Environ Health Perspect. 1991 Jan;90:35-41
pubmed: 2050081
PLoS One. 2012;7(12):e52302
pubmed: 23300636
C R Acad Sci III. 1996 Oct;319(10):887-92
pubmed: 8977769
Sci Total Environ. 2012 May 1;424:130-42
pubmed: 22425172
Lipids. 2014 Aug;49(8):807-18
pubmed: 24934587
J Invertebr Pathol. 2015 Oct;131:83-106
pubmed: 26146225
Dis Aquat Organ. 2005 Aug 9;66(1):41-6
pubmed: 16175967
Dis Aquat Organ. 2010 Jul 1;90(3):215-22
pubmed: 20815330
Mar Pollut Bull. 2019 Feb;139:238-255
pubmed: 30686425
J Natl Cancer Inst. 1974 Jun;52(6):1739-49
pubmed: 4834406
Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):14175-80
pubmed: 25201971
Zootaxa. 2021 Oct 18;5052(4):579-584
pubmed: 34810854
Aquat Toxicol. 2013 Jul 15;136-137:101-11
pubmed: 23665240
J Invertebr Pathol. 2006 Nov;93(3):207-9
pubmed: 16996536
Evolution. 2009 Sep;63(9):2340-9
pubmed: 19453727
PLoS One. 2017 Mar 10;12(3):e0173219
pubmed: 28282459
Dis Aquat Organ. 2005 Jul 18;65(3):187-95
pubmed: 16119887
Dis Aquat Organ. 2020 Feb 27;138:89-96
pubmed: 32103823
Mar Genomics. 2018 Jul;40:58-63
pubmed: 29657123
Dev Comp Immunol. 2019 Mar;92:260-282
pubmed: 30503358
Nature. 2006 Feb 2;439(7076):549
pubmed: 16452970
Pathogens. 2022 Feb 23;11(3):
pubmed: 35335607
Mol Ecol. 2022 Feb;31(3):736-751
pubmed: 34192383
Proc Natl Acad Sci U S A. 2018 May 1;115(18):E4227-E4235
pubmed: 29669918
J Invertebr Pathol. 2015 Oct;131:107-20
pubmed: 26215472
J Invertebr Pathol. 2016 Jul;138:30-8
pubmed: 27264803
Mamm Genome. 2011 Feb;22(1-2):83-90
pubmed: 20963591
Nature. 2016 Jun 30;534(7609):705-9
pubmed: 27338791
Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):374-9
pubmed: 26711993
Cell. 2006 Aug 11;126(3):477-87
pubmed: 16901782
Mol Mar Biol Biotechnol. 1994 Oct;3(5):294-9
pubmed: 7881515
Sci Rep. 2021 Mar 11;11(1):5809
pubmed: 33707525
Cell. 2015 Apr 9;161(2):255-63
pubmed: 25860608
Dis Aquat Organ. 2013 Jul 9;105(1):81-7
pubmed: 23836773
Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):18018-23
pubmed: 23043118
Mar Pollut Bull. 2004 Aug;49(3):264-76
pubmed: 15245990
J Invertebr Pathol. 2006 Jun;92(2):79-84
pubmed: 16723136
Syst Biol. 2010 May;59(3):307-21
pubmed: 20525638