Willingness to participate in various nontherapeutic cancer research activities among urban and rural African American and Latinx healthy volunteers.
Healthy volunteers
Minority health disparities
Nontherapeutic clinical research
Participation willingness
Rural health
Journal
Cancer causes & control : CCC
ISSN: 1573-7225
Titre abrégé: Cancer Causes Control
Pays: Netherlands
ID NLM: 9100846
Informations de publication
Date de publication:
Aug 2022
Aug 2022
Historique:
received:
27
10
2020
accepted:
18
03
2022
pubmed:
12
4
2022
medline:
14
7
2022
entrez:
11
4
2022
Statut:
ppublish
Résumé
Inclusion of racial/ethnic minorities in cancer research can reduce disparities in health outcomes; however, data regarding barriers and motivators to participation are sparse. This study assessed African American (AA) and Latinx healthy volunteers' perspectives regarding willingness to participate in noninvasive and invasive research activities. Using a 38-item questionnaire adapted from the Tuskegee Legacy Project Questionnaire, we assessed willingness to participate in 12 research activities, offering 27 possible barriers and 14 motivators. The sample was segmented into four subgroups by AA/Latinx and rural/urban. Across five states and Puerto Rico, 533 participants completed questionnaires. Overall, participants were more willing to participate in noninvasive versus invasive procedures, although, all subgroups were willing to participate in research if asked. Rural AA were most willing to complete a survey or saliva sample, while rural Latinx were least willing. Urban AA were least willing to provide cheek swab, while rural counterparts were most willing. Self-benefit and benefit to others were among the top three motivators for all subgroups. Curiosity was a primary motivator for urban AA while obtaining health information motivated rural Latinx. Primary barriers included fears of side effects and being experimented on, lack of information, and lack of confidentiality. Latinx and AAs are willing to participate in the continuum of nontherapeutic research activities suggesting their lack of participation may be related to not being asked. Inclusive enrollment may be achieved by assessing needs of participants during the design phase of a study in order to reduce barriers to participation.
Identifiants
pubmed: 35404020
doi: 10.1007/s10552-022-01576-9
pii: 10.1007/s10552-022-01576-9
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1059-1069Subventions
Organisme : NCI NIH HHS
ID : U54CA153719
Pays : United States
Organisme : NCI NIH HHS
ID : U54CA153719
Pays : United States
Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer Nature Switzerland AG.
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