Bothrops leucurus snake venom protein profile, isolation and biological characterization of its major toxin PLA

Animals Antivenins / pharmacology Bothrops / metabolism Crotalid Venoms / metabolism Phospholipases A2 / metabolism Snake Venoms / metabolism
Bothrops leucurus Mass spectrometry Phospholipase A(2) Proteome Snake venom

Journal

Toxicon : official journal of the International Society on Toxinology
ISSN: 1879-3150
Titre abrégé: Toxicon
Pays: England
ID NLM: 1307333

Informations de publication

Date de publication:
15 Jul 2022
Historique:
received: 17 01 2022
revised: 02 04 2022
accepted: 04 04 2022
pubmed: 12 4 2022
medline: 19 5 2022
entrez: 11 4 2022
Statut: ppublish

Résumé

Bothrops leucurus is considered as a snake of medical interest in the State of Bahia, Brazil. However, so far, there are no studies that provide a refined mapping of the composition of this venom. The aim of this work was to better understand the protein composition of B. leucurus snake venom and to isolate and biologically characterize the most abundant toxin, a basic PLA

Identifiants

DOI: 10.1016/j.toxicon.2022.04.002 PMID: 35405203
pubmed: 35405203
pii: S0041-0101(22)00096-4
doi: 10.1016/j.toxicon.2022.04.002
pii:
doi:

Substances chimiques

Antivenins 0
Crotalid Venoms 0
Snake Venoms 0
Phospholipases A2 EC 3.1.1.4

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

27-42

Informations de copyright

Copyright © 2022 Elsevier Ltd. All rights reserved.

Auteurs

Êuder Reis Dias (ÊR)

Graduate Program in Biotechnology, State University of Feira de Santana (UEFS), Feira de Santana, BA, Brazil.

Laudicéia Alves de Oliveira (LA)

Graduate Program in Tropical Diseases, Botucatu Medical School (FMB), São Paulo State University (UNESP), Botucatu, SP, Brazil.

Pedro Santana Sales Lauria (PSS)

Laboratory of Pharmacology and Experimental Therapeutics, College of Pharmacy, Federal University of Bahia, Salvador, BA, Brazil.

Karla de Castro Figueiredo Bordon (KCF)

Department of BioMolecular Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.

Adriana Moraes Rodrigues Domênico (AM)

Specialization in Diagnostic and Therapeutic Innovations, Hospital das Clínicas, São Paulo State University (UNESP), Botucatu, SP, Brazil.

Marcos Lázaro da Silva Guerreiro (ML)

Laboratory of Venomous Animals and Herpetology, State University of Feira de Santana, Feira de Santana, BA, Brazil.

Gisele Adriano Wiezel (GA)

Department of BioMolecular Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.

Iara Aimê Cardoso (IA)

Department of BioMolecular Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.

Bruno César Rossini (BC)

Biotechnology Institute (IBTEC), São Paulo State University (UNESP), Botucatu, SP, Brazil; Department of Biological and Chemical Sciences, São Paulo State University (UNESP), Botucatu, SP, Brazil.

Celso Luís Marino (CL)

Biotechnology Institute (IBTEC), São Paulo State University (UNESP), Botucatu, SP, Brazil; Department of Biological and Chemical Sciences, São Paulo State University (UNESP), Botucatu, SP, Brazil.

Daniel Carvalho Pimenta (DC)

Laboratory of Biochemistry and Biophysics, Butantan Institute, São Paulo, SP, Brazil.

Eliane Candiani Arantes (EC)

Department of BioMolecular Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.

Luciana Lyra Casais-E-Silva (LL)

Laboratory of Neuroimmunoendocrinology and Toxinology, Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil.

Alexsandro Branco (A)

Graduate Program in Biotechnology, State University of Feira de Santana (UEFS), Feira de Santana, BA, Brazil; Health Department, State University of Feira de Santana, Feira de Santana, BA, Brazil.

Lucilene Delazari Dos Santos (LD)

Graduate Program in Tropical Diseases, Botucatu Medical School (FMB), São Paulo State University (UNESP), Botucatu, SP, Brazil; Specialization in Diagnostic and Therapeutic Innovations, Hospital das Clínicas, São Paulo State University (UNESP), Botucatu, SP, Brazil; Biotechnology Institute (IBTEC), São Paulo State University (UNESP), Botucatu, SP, Brazil; Graduate Program in Graduate Program in Research and Development (Medical Biotechnology), Botucatu Medical School (FMB), São Paulo State University (UNESP), Botucatu, SP, Brazil. Electronic address: lucilene.delazari@unesp.br.

Ilka Biondi (I)

Laboratory of Venomous Animals and Herpetology, State University of Feira de Santana, Feira de Santana, BA, Brazil. Electronic address: ibiondi@uefs.br.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Bothrops leucurus snake venom protein profile,...
questionsmedicales.fr › Mélanges complexes › Produits biologiques › Sérums immuns › Antitoxines › Sérums antivenimeux › Bothrops leucurus snake venom protein profile,...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Reptiles › Serpents › Alethinophidia › Viperidae › Crotalinae › Bothrops › Bothrops leucurus snake venom protein profile,...
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Venins › Venins de serpent › Venins de vipère › Venins de crotalidé › Bothrops leucurus snake venom protein profile,...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Esterases › Carboxylic ester hydrolases › Phospholipases A › Phospholipases A2 › Bothrops leucurus snake venom protein profile,...
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Venins › Venins de serpent › Bothrops leucurus snake venom protein profile,...