Application of Green Gold Nanoparticles in Cancer Therapy and Diagnosis.
biosynthesis
gold nanoparticles
green synthesis
leaf extract
surface plasmon resonance
toxicity
Journal
Nanomaterials (Basel, Switzerland)
ISSN: 2079-4991
Titre abrégé: Nanomaterials (Basel)
Pays: Switzerland
ID NLM: 101610216
Informations de publication
Date de publication:
27 Mar 2022
27 Mar 2022
Historique:
received:
23
02
2022
revised:
22
03
2022
accepted:
23
03
2022
entrez:
12
4
2022
pubmed:
13
4
2022
medline:
13
4
2022
Statut:
epublish
Résumé
Nanoparticles are currently used for cancer theranostics in the clinical field. Among nanoparticles, gold nanoparticles (AuNPs) attract much attention due to their usability and high performance in imaging techniques. The wide availability of biological precursors used in plant-based synthesized AuNPs allows for the development of large-scale production in a greener manner. Conventional cancer therapies, such as surgery and chemotherapy, have significant limitations and frequently fail to produce satisfying results. AuNPs have a prolonged circulation time, allow easy modification with ligands detected via cancer cell surface receptors, and increase uptake through receptor-mediated endocytosis. To exploit these unique features, studies have been carried out on the use of AuNPs as contrast agents for X-ray-based imaging techniques (i.e., computed tomography). As nanocarriers, AuNPs synthesized by nontoxic and biocompatible plants to deliver therapeutic biomolecules could be a significant stride forward in the effective treatment of various cancers. Fluorescent-plant-based markers, including AuNPs, fabricated using
Identifiants
pubmed: 35407220
pii: nano12071102
doi: 10.3390/nano12071102
pmc: PMC9000429
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Subventions
Organisme : Community of Madrid
ID : EPU-INV/2020/012
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