Targeting C-Reactive Protein by Selective Apheresis in Humans: Pros and Cons.
COVID-19
arteriosclerosis
cardiovascular
inflammation
ischemic stroke
therapeutic apheresis
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
23 Mar 2022
23 Mar 2022
Historique:
received:
17
02
2022
revised:
13
03
2022
accepted:
17
03
2022
entrez:
12
4
2022
pubmed:
13
4
2022
medline:
13
4
2022
Statut:
epublish
Résumé
C-reactive protein (CRP), the prototype human acute phase protein, may be causally involved in various human diseases. As CRP has appeared much earlier in evolution than antibodies and nonetheless partly utilizes the same biological structures, it is likely that CRP has been the first antibody-like molecule in the evolution of the immune system. Like antibodies, CRP may cause autoimmune reactions in a variety of human pathologies. Consequently, therapeutic targeting of CRP may be of utmost interest in human medicine. Over the past two decades, however, pharmacological targeting of CRP has turned out to be extremely difficult. Currently, the easiest, most effective and clinically safest method to target CRP in humans may be the specific extracorporeal removal of CRP by selective apheresis. The latter has recently shown promising therapeutic effects, especially in acute myocardial infarction and COVID-19 pneumonia. This review summarizes the pros and cons of applying this novel technology to patients suffering from various diseases, with a focus on its use in cardiovascular medicine.
Identifiants
pubmed: 35407379
pii: jcm11071771
doi: 10.3390/jcm11071771
pmc: PMC8999816
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Arterioscler Thromb Vasc Biol. 2004 Dec;24(12):2372-7
pubmed: 15486314
Eur Heart J. 2017 Dec 14;38(47):3502-3510
pubmed: 29020248
JAMA. 2020 Apr 7;323(13):1239-1242
pubmed: 32091533
Am J Case Rep. 2021 Aug 05;22:e932964
pubmed: 34351878
BMJ. 2011 Feb 15;342:d548
pubmed: 21325005
Mediators Inflamm. 2014;2014:353614
pubmed: 24803739
J Immunol. 2001 Feb 15;166(4):2378-84
pubmed: 11160296
Nat Clin Pract Nephrol. 2008 May;4(5):234-5
pubmed: 18317503
Case Rep Cardiol. 2018 Nov 6;2018:4767105
pubmed: 30533227
J Am Coll Cardiol. 2006 Mar 7;47(5):962-8
pubmed: 16516078
J Infect. 2021 Apr;82(4):1-10
pubmed: 33610683
Pharmacol Ther. 2018 Jun;186:73-87
pubmed: 29330085
Int J Epidemiol. 2004 Feb;33(1):30-42
pubmed: 15075143
Ther Apher Dial. 2019 Oct;23(5):474-481
pubmed: 30697961
Stroke. 2002 Oct;33(10):2459-64
pubmed: 12364738
Arterioscler Thromb Vasc Biol. 1998 Sep;18(9):1386-92
pubmed: 9743226
J Artif Organs. 2003;6(1):1-8
pubmed: 14598117
Eur Heart J. 2021 Jun 14;42(23):2280-2283
pubmed: 33778886
J Immunol. 1976 Sep;117(3):774-81
pubmed: 60448
N Engl J Med. 2008 Oct 30;359(18):1897-908
pubmed: 18971492
Nature. 2006 Apr 27;440(7088):1217-21
pubmed: 16642000
Cell Rep Med. 2020 Nov 17;1(8):100144
pubmed: 33163981
Atheroscler Suppl. 2019 Dec;40:23-29
pubmed: 31818446
N Engl J Med. 2019 Dec 26;381(26):2497-2505
pubmed: 31733140
Ther Apher Dial. 2019 Dec;23(6):570-574
pubmed: 30924312
Int J Epidemiol. 2003 Feb;32(1):1-22
pubmed: 12689998
JAMA. 2009 Jul 1;302(1):37-48
pubmed: 19567438
J Cereb Blood Flow Metab. 2004 Nov;24(11):1214-8
pubmed: 15545914
J Exp Med. 1999 Aug 16;190(4):585-90
pubmed: 10449529
N Engl J Med. 2008 Nov 20;359(21):2195-207
pubmed: 18997196
J Immunol. 2008 Aug 15;181(4):2420-7
pubmed: 18684932
J Med Virol. 2020 Jul;92(7):856-862
pubmed: 32281668
Am J Pathol. 2003 Jul;163(1):269-75
pubmed: 12819031
J Med Virol. 2020 Oct;92(10):2188-2192
pubmed: 32436996
Circulation. 1997 Jan 7;95(1):97-103
pubmed: 8994423
Front Cardiovasc Med. 2021 Mar 10;8:591714
pubmed: 33778017
Stroke. 2001 Jan;32(1):133-8
pubmed: 11136928
Stroke. 1999 May;30(5):981-5
pubmed: 10229731
Eur Heart J. 2021 Jun 14;42(23):2270-2279
pubmed: 33448289
Intensive Care Med. 2020 May;46(5):846-848
pubmed: 32125452
J Clin Virol. 2020 Jun;127:104370
pubmed: 32344321
Ther Apher Dial. 2019 Dec;23(6):494-496
pubmed: 31788974
Arterioscler Thromb Vasc Biol. 2004 Oct;24(10):e168-71
pubmed: 15319265
JAMA Cardiol. 2019 Apr 1;4(4):314-320
pubmed: 30840024
Neurotherapeutics. 2016 Oct;13(4):661-670
pubmed: 27730544
Cardiovasc Res. 2002 Jan;53(1):31-47
pubmed: 11744011
Arterioscler Thromb Vasc Biol. 2005 Jun;25(6):1225-30
pubmed: 15802626
Arch Intern Med. 2006 Oct 23;166(19):2073-80
pubmed: 17060536
Front Immunol. 2018 Apr 13;9:754
pubmed: 29706967
Am J Case Rep. 2020 Jul 14;21:e925020
pubmed: 32661220
J Biol Chem. 1986 Aug 5;261(22):10450-5
pubmed: 3015932
Gastroenterology. 2008 Aug;135(2):400-9
pubmed: 18602921
J Immunol. 2007 Jun 1;178(11):7302-9
pubmed: 17513780
Annu Rev Immunol. 1997;15:203-34
pubmed: 9143687
J Clin Med. 2020 Sep 12;9(9):
pubmed: 32932587
Mediators Inflamm. 2014;2014:561428
pubmed: 24799767
N Engl J Med. 2008 Oct 30;359(18):1953-5
pubmed: 18971498
Front Cardiovasc Med. 2022 Mar 24;9:797116
pubmed: 35402541
Front Immunol. 2021 Aug 02;12:708101
pubmed: 34408751
Ther Apher Dial. 2021 Apr;25(2):251-252
pubmed: 32501607
Am J Case Rep. 2022 Jan 10;23:e935263
pubmed: 35007274
J Clin Invest. 2003 Jun;111(12):1805-12
pubmed: 12813013
N Engl J Med. 2017 Sep 21;377(12):1119-1131
pubmed: 28845751
Int J Infect Dis. 2020 Jun;95:304-307
pubmed: 32344011
J Clin Apher. 2015 Feb;30(1):15-21
pubmed: 25044559
Circulation. 2003 Jan 28;107(3):499-511
pubmed: 12551878
Nat Commun. 2020 Oct 8;11(1):5086
pubmed: 33033248
Life Sci. 2004 Jul 9;75(8):901-10
pubmed: 15193950
Mediators Inflamm. 2014;2014:683598
pubmed: 24872599
Circulation. 2021 Mar 30;143(13):1338-1340
pubmed: 33587646
Immunol Res. 1997;16(2):127-36
pubmed: 9212359
Biochem Biophys Res Commun. 2010 Mar 26;394(1):233-9
pubmed: 20206126
Mediators Inflamm. 2014;2014:646817
pubmed: 24976688
Eur Heart J. 1997 Nov;18(11):1834-6
pubmed: 9402460
Biomed Rep. 2016 Dec;5(6):761-765
pubmed: 28105343
Lancet. 2020 Mar 28;395(10229):1033-1034
pubmed: 32192578
N Engl J Med. 2009 Feb 26;360(9):934; author reply 934-5
pubmed: 19256031
Basic Res Cardiol. 2009 Sep;104(5):591-9
pubmed: 19343415
J Exp Med. 1999 Dec 20;190(12):1733-40
pubmed: 10601349
J Pharmacol Exp Ther. 2002 Dec;303(3):1007-13
pubmed: 12438521
Curr Opin Rheumatol. 2021 Jan;33(1):8-14
pubmed: 33164993
N Engl J Med. 2020 May 21;382(21):2012-2022
pubmed: 32227758
Circ Res. 2017 Feb 3;120(3):541-558
pubmed: 28154103
Nat Rev Cardiol. 2021 Mar;18(3):169-193
pubmed: 33046850
Cytokine. 2011 Dec;56(3):850-4
pubmed: 21967870
Stroke. 2005 Jun;36(6):1316-29
pubmed: 15879341
Arthritis Rheum. 2003 Jun;48(6):1475-7
pubmed: 12794811
Gut. 2013 Sep;62(9):1288-94
pubmed: 22760005
Front Immunol. 2021 Feb 10;12:630430
pubmed: 33679775
Clin Chem. 2010 Mar;56(3):388-90
pubmed: 20093553
Rev Med Virol. 2021 Nov;31(6):e2221
pubmed: 34773448
J Immunol. 1974 Jun;112(6):2135-47
pubmed: 4151108
Stroke. 2006 May;37(5):1205-10
pubmed: 16601211