Diagnostic and Therapeutic Potential for HNP-1, HBD-1 and HBD-4 in Pregnant Women with COVID-19.
COVID-19
biochemistry
coagulation
defensins
immune system
interleukins
laboratory medicine
lipoprotein-a
pregnancy
vitamins
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
22 Mar 2022
22 Mar 2022
Historique:
received:
25
02
2022
revised:
18
03
2022
accepted:
19
03
2022
entrez:
12
4
2022
pubmed:
13
4
2022
medline:
14
4
2022
Statut:
epublish
Résumé
Pregnancy is characterized by significant immunological changes and a cytokine profile, as well as vitamin deficiencies that can cause problems for the correct development of a fetus. Defensins are small antimicrobial peptides that are part of the innate immune system and are involved in several biological activities. Following that, this study aims to compare the levels of various cytokines and to investigate the role of defensins between pregnant women with confirmed COVID-19 infection and pregnant women without any defined risk factor. TNF-α, TGF-β, IL-2 and IL-10, β-defensins, have been evaluated by gene expression in our population. At the same time, by
Identifiants
pubmed: 35408809
pii: ijms23073450
doi: 10.3390/ijms23073450
pmc: PMC8998699
pii:
doi:
Substances chimiques
Cytokines
0
Interleukin-2
0
Interleukin-6
0
Interleukin-8
0
Transforming Growth Factor beta
0
Tumor Necrosis Factor-alpha
0
alpha-Defensins
0
beta-Defensins
0
human neutrophil peptide 1
0
Interleukin-10
130068-27-8
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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