The Interplay of Cohesin and RNA Processing Factors: The Impact of Their Alterations on Genome Stability.
RNA processing factors
chromosome segregation
cohesin
genome stability
sororin
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
01 Apr 2022
01 Apr 2022
Historique:
received:
03
03
2022
revised:
28
03
2022
accepted:
31
03
2022
entrez:
12
4
2022
pubmed:
13
4
2022
medline:
14
4
2022
Statut:
epublish
Résumé
Cohesin, a multi-subunit protein complex, plays important roles in sister chromatid cohesion, DNA replication, chromatin organization, gene expression, transcription regulation, and the recombination or repair of DNA damage. Recently, several studies suggested that the functions of cohesin rely not only on cohesin-related protein-protein interactions, their post-translational modifications or specific DNA modifications, but that some RNA processing factors also play an important role in the regulation of cohesin functions. Therefore, the mutations and changes in the expression of cohesin subunits or alterations in the interactions between cohesin and RNA processing factors have been shown to have an impact on cohesion, the fidelity of chromosome segregation and, ultimately, on genome stability. In this review, we provide an overview of the cohesin complex and its role in chromosome segregation, highlight the causes and consequences of mutations and changes in the expression of cohesin subunits, and discuss the RNA processing factors that participate in the regulation of the processes involved in chromosome segregation. Overall, an understanding of the molecular determinants of the interplay between cohesin and RNA processing factors might help us to better understand the molecular mechanisms ensuring the integrity of the genome.
Identifiants
pubmed: 35409298
pii: ijms23073939
doi: 10.3390/ijms23073939
pmc: PMC8999970
pii:
doi:
Substances chimiques
Cell Cycle Proteins
0
Chromosomal Proteins, Non-Histone
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Slovak Research and Development Agency
ID : APVV-20-0141
Organisme : Slovak Grant Agency VEGA
ID : 2/0039/19
Organisme : Slovak Grant Agency VEGA
ID : 2/0021/22
Références
Curr Biol. 2012 Apr 10;22(7):R240-50
pubmed: 22497943
EMBO J. 2016 Dec 15;35(24):2686-2698
pubmed: 27872142
Semin Cell Dev Biol. 2019 Jun;90:187-193
pubmed: 30096363
Blood. 2012 Nov 1;120(18):e83-92
pubmed: 22976956
Biology (Basel). 2017 Feb 08;6(1):
pubmed: 28208750
Onco Targets Ther. 2016 Apr 15;9:2211-20
pubmed: 27143916
Science. 2011 Aug 19;333(6045):1039-43
pubmed: 21852505
Nat Genet. 2018 Mar;50(3):329-332
pubmed: 29379197
Curr Opin Cell Biol. 2018 Jun;52:51-57
pubmed: 29433064
Oncol Lett. 2020 May;19(5):3506-3512
pubmed: 32269624
G3 (Bethesda). 2014 Jun 19;4(8):1555-64
pubmed: 24948787
Int J Mol Sci. 2021 May 30;22(11):
pubmed: 34070827
Science. 2019 Dec 13;366(6471):1338-1345
pubmed: 31753851
Genes Dev. 2009 Sep 15;23(18):2224-36
pubmed: 19696148
Nat Genet. 2004 Nov;36(11):1159-61
pubmed: 15475955
Nat Genet. 2005 May;37(5):468-70
pubmed: 15821733
Genes (Basel). 2018 Nov 28;9(12):
pubmed: 30487431
Nat Genet. 2016 Oct;48(10):1112-8
pubmed: 27618451
Hum Mol Genet. 2008 Jul 15;17(14):2172-80
pubmed: 18411254
Mol Cell. 2005 Apr 15;18(2):185-200
pubmed: 15837422
Am J Hum Genet. 1992 Nov;51(5):1136-49
pubmed: 1415255
J Biol Chem. 2019 May 31;294(22):8760-8772
pubmed: 31010829
EMBO Rep. 2014 Sep;15(9):956-64
pubmed: 25092792
Mol Cell. 2004 Dec 22;16(6):1003-15
pubmed: 15610742
Int J Cancer. 2019 Jan 1;144(1):8-25
pubmed: 29981145
Cell. 2000 Oct 27;103(3):399-410
pubmed: 11081627
Genes Chromosomes Cancer. 2004 Jan;39(1):1-10
pubmed: 14603436
J Appl Genet. 2019 May;60(2):231
pubmed: 30888641
Cell Prolif. 2011 Oct;44(5):391-400
pubmed: 21951282
PLoS One. 2013 Sep 19;8(9):e74851
pubmed: 24069358
Nucleic Acids Res. 2019 Jul 26;47(13):6956-6972
pubmed: 31175837
Mutat Res. 2010 Dec;705(3):246-51
pubmed: 20932937
J Cell Biol. 2008 Jan 28;180(2):315-24
pubmed: 18227278
Curr Opin Cell Biol. 2019 Jun;58:8-14
pubmed: 30544080
Science. 2001 Aug 17;293(5533):1320-3
pubmed: 11509732
EMBO Rep. 2018 Jan;19(1):43-56
pubmed: 29138236
Cancer Cell. 2018 Apr 9;33(4):676-689.e3
pubmed: 29622463
Genet Mol Res. 2015 Mar 30;14(1):2638-46
pubmed: 25867412
Elife. 2017 Sep 15;6:
pubmed: 28914604
Epigenetics Chromatin. 2020 Aug 10;13(1):32
pubmed: 32778134
Biochim Biophys Acta. 2016 Aug;1866(1):1-11
pubmed: 27207471
Cell. 2018 Jan 25;172(3):465-477.e15
pubmed: 29358048
Am J Hum Genet. 2007 Mar;80(3):485-94
pubmed: 17273969
J Cell Sci. 2011 Sep 1;124(Pt 17):2976-87
pubmed: 21878504
Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3443-8
pubmed: 18299561
Cell. 2012 Jul 20;150(2):264-78
pubmed: 22817890
Nature. 2014 Jan 16;505(7483):367-71
pubmed: 24291789
Am J Hum Genet. 2010 Feb 12;86(2):262-6
pubmed: 20137776
Mol Cell Biol. 2015 Feb;35(4):634-48
pubmed: 25452306
Mol Cell. 2008 Jul 11;31(1):47-56
pubmed: 18614046
Int J Biochem Cell Biol. 2017 Oct;91(Pt B):168-175
pubmed: 28743674
Genome Res. 2020 Apr;30(4):515-527
pubmed: 32253279
Nat Genet. 2013 Dec;45(12):1459-63
pubmed: 24121792
Mol Biol Cell. 2006 Oct;17(10):4187-99
pubmed: 16855028
Genes Dev. 2020 Oct 1;34(19-20):1392-1405
pubmed: 32883681
Elife. 2017 Jul 10;6:
pubmed: 28691904
J Med Genet. 2020 May;57(5):289-295
pubmed: 31704779
Trends Cell Biol. 2011 Jun;21(6):374-81
pubmed: 21306900
Nat Genet. 2004 Jun;36(6):636-41
pubmed: 15146185
Cell. 2019 Oct 17;179(3):604-618
pubmed: 31607512
Curr Biol. 2012 Apr 10;22(7):638-44
pubmed: 22405866
J Cell Sci. 2017 Feb 15;130(4):767-778
pubmed: 28062851
Elife. 2021 Jul 26;10:
pubmed: 34309513
Elife. 2020 Apr 06;9:
pubmed: 32250245
Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13404-9
pubmed: 23901111
FEBS Lett. 2013 Aug 2;587(15):2299-312
pubmed: 23831059
Nature. 2010 Apr 1;464(7289):721-7
pubmed: 20360735
Curr Biol. 2006 Aug 8;16(15):1571-8
pubmed: 16890534
Elife. 2018 Nov 26;7:
pubmed: 30475206
J Cell Sci. 2007 Jul 1;120(Pt 13):2139-42
pubmed: 17591686
Nature. 2014 Jan 23;505(7484):495-501
pubmed: 24390350
Cell. 2018 May 31;173(6):1508-1519.e18
pubmed: 29754816
Nat Commun. 2021 Jul 27;12(1):4551
pubmed: 34315879
Mol Cell. 2019 Jul 25;75(2):324-339.e11
pubmed: 31155380
EMBO J. 2012 May 2;31(9):2076-89
pubmed: 22415365
EMBO Rep. 2014 Sep;15(9):948-55
pubmed: 25092791
EMBO J. 2017 Dec 15;36(24):3573-3599
pubmed: 29217591
Trends Genet. 2020 Jun;36(6):387-389
pubmed: 32396831
J Biol Chem. 2011 Feb 4;286(5):3579-86
pubmed: 21115494
Cold Spring Harb Perspect Med. 2017 Jan 3;7(1):
pubmed: 28049655
Science. 2007 Jul 13;317(5835):245-8
pubmed: 17626885
Cell. 1997 Oct 3;91(1):35-45
pubmed: 9335333
Elife. 2014 May 6;:e02028
pubmed: 24842991
Hum Mol Genet. 2014 Dec 20;23(25):6773-8
pubmed: 25080505
Cell Rep. 2020 Mar 10;30(10):3368-3382.e7
pubmed: 32160543
Curr Opin Genet Dev. 2020 Apr;61:9-16
pubmed: 32294612
Curr Biol. 2006 Dec 19;16(24):2406-17
pubmed: 17112726
Oncotarget. 2017 Jun 6;8(23):37619-37632
pubmed: 28430577
Curr Opin Genet Dev. 2018 Feb;48:67-74
pubmed: 29136527
Science. 2008 Jul 25;321(5888):563-6
pubmed: 18653893
Nat Genet. 2013 Dec;45(12):1464-9
pubmed: 24121791
Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):17974-8
pubmed: 21997207
Annu Rev Biochem. 2020 Jun 20;89:103-133
pubmed: 32176524
J Cell Sci. 2013 Aug 1;126(Pt 15):3493-503
pubmed: 23729739
Mutat Res Rev Mutat Res. 2020 Jul - Sep;785:108320
pubmed: 32800274
Elife. 2018 Aug 15;7:
pubmed: 30109982
Cell. 2006 Dec 1;127(5):955-67
pubmed: 17113138
Nat Genet. 2006 May;38(5):528-30
pubmed: 16604071
Sci Rep. 2020 Jan 17;10(1):592
pubmed: 31953484
Nat Commun. 2018 Oct 12;9(1):4234
pubmed: 30315276
Nat Commun. 2020 Jul 3;11(1):3321
pubmed: 32620872
Nature. 1999 Jul 1;400(6739):37-42
pubmed: 10403247
PLoS Genet. 2016 Feb 12;12(2):e1005865
pubmed: 26871722
Nat Cell Biol. 2011 Jul 10;13(8):966-72
pubmed: 21743463
Cells. 2021 Dec 08;10(12):
pubmed: 34943967
J Exp Clin Cancer Res. 2021 Mar 1;40(1):82
pubmed: 33648524
Nat Rev Cancer. 2020 Sep;20(9):504-515
pubmed: 32514055
Mol Cell Biol. 2002 Feb;22(3):801-15
pubmed: 11784857
Curr Genet. 2021 Jun;67(3):447-459
pubmed: 33404730
Exp Hematol Oncol. 2014 May 08;3:13
pubmed: 24904756
Genes Dev. 1999 Apr 1;13(7):841-50
pubmed: 10197984
Science. 2019 Dec 13;366(6471):1345-1349
pubmed: 31780627
PLoS One. 2014 Feb 28;9(2):e89976
pubmed: 24587161
Nat Genet. 2013 Oct;45(10):1232-7
pubmed: 23955599
Dig Dis Sci. 2016 Mar;61(3):795-805
pubmed: 26553251
Gene. 2020 Oct 20;758:144966
pubmed: 32687945
Mol Cancer. 2018 Feb 15;17(1):23
pubmed: 29448935
Int J Mol Med. 2011 Jan;27(1):39-51
pubmed: 21069257
Biomed Pharmacother. 2018 Aug;104:788-797
pubmed: 29852353
J Exp Clin Cancer Res. 2019 Mar 1;38(1):108
pubmed: 30823889
EMBO J. 2014 Nov 18;33(22):2643-58
pubmed: 25257309
EMBO J. 2016 Mar 15;35(6):635-53
pubmed: 26903600
Cold Spring Harb Perspect Biol. 2011 Jul 01;3(7):
pubmed: 21441581
J Cell Sci. 2021 Jan 8;134(1):
pubmed: 33419949
J Cell Biol. 2001 Apr 30;153(3):517-27
pubmed: 11331303
Elife. 2019 Jun 17;8:
pubmed: 31204999
Nature. 2021 Feb;590(7847):660-665
pubmed: 33597753
EMBO J. 2021 Jul 15;40(14):e106536
pubmed: 34009673
PLoS Genet. 2014 Jul 10;10(7):e1004475
pubmed: 25010205
Annu Rev Genet. 2019 Dec 3;53:445-482
pubmed: 31577909
Biochim Biophys Acta. 2008 Sep;1786(1):41-8
pubmed: 18474253
Nat Cell Biol. 2021 Nov;23(11):1176-1186
pubmed: 34750581
EMBO J. 2015 Jan 2;34(1):115-29
pubmed: 25398909
Nature. 2004 Dec 23;432(7020):1036-40
pubmed: 15616564
J Cell Sci. 2020 May 22;133(10):
pubmed: 32299836
Int J Biol Sci. 2018 Jun 8;14(9):1081-1089
pubmed: 29988990
Appl Clin Genet. 2013 May 01;6:15-23
pubmed: 23882154
Curr Biol. 2018 Nov 5;28(21):R1266-R1281
pubmed: 30399354
Clin Genet. 2015 Nov;88(5):405-15
pubmed: 25865758
PLoS Biol. 2020 Jan 2;18(1):e3000594
pubmed: 31895940
Cell Cycle. 2015;14(6):820-6
pubmed: 25608232
Curr Biol. 2012 Nov 20;22(22):R966-80
pubmed: 23174302
Cell. 2003 Mar 21;112(6):765-77
pubmed: 12654244
Curr Opin Struct Biol. 2018 Apr;49:114-122
pubmed: 29452922
Science. 2002 Dec 13;298(5601):2205-8
pubmed: 12411573
Cold Spring Harb Perspect Biol. 2016 Sep 01;8(9):
pubmed: 27587616
Nat Genet. 2021 Jan;53(1):100-109
pubmed: 33318687
Trends Cell Biol. 2021 Sep;31(9):760-773
pubmed: 33766521
Bioessays. 2018 Oct;40(10):e1800109
pubmed: 30106480
Science. 2007 Apr 20;316(5823):417-21
pubmed: 17412918
Nat Genet. 2004 Jun;36(6):631-5
pubmed: 15146186
Curr Biol. 2017 Apr 3;27(7):992-1004
pubmed: 28343965
Mol Cell. 2000 Feb;5(2):243-54
pubmed: 10882066
Wiley Interdiscip Rev Dev Biol. 2015 Sep-Oct;4(5):489-504
pubmed: 25847322
EMBO J. 2014 Nov 18;33(22):2623-42
pubmed: 25257310
Genetics. 2021 Apr 15;217(4):
pubmed: 33704438
Genome Res. 2013 Dec;23(12):2066-77
pubmed: 24002784
Curr Cancer Drug Targets. 2001 May;1(1):73-83
pubmed: 12188893
AIMS Mol Sci. 2016;3(4):597-634
pubmed: 28920074
J Cell Biol. 1995 Aug;130(4):941-8
pubmed: 7642709
Nature. 2004 Feb 5;427(6974):510-7
pubmed: 14730319
J Med Genet. 2014 Oct;51(10):659-68
pubmed: 25125236
Cancers (Basel). 2020 Aug 06;12(8):
pubmed: 32781708
Int J Mol Sci. 2017 Apr 07;18(4):
pubmed: 28387715
Chromosome Res. 2016 Jan;24(1):5-17
pubmed: 26658800
Cell Death Dis. 2014 Mar 27;5:e1151
pubmed: 24675469
Mol Biol Cell. 2012 Feb;23(3):401-11
pubmed: 22130796
Curr Biol. 2007 Apr 3;17(7):630-6
pubmed: 17349791
Science. 2020 Jun 26;368(6498):1454-1459
pubmed: 32409525
Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):17108-13
pubmed: 15563594
Cell Cycle. 2019 Nov;18(21):2828-2848
pubmed: 31516082
Nucleic Acids Res. 2019 Apr 23;47(7):3450-3466
pubmed: 30657957
Elife. 2020 Sep 15;9:
pubmed: 32930661
PLoS Genet. 2021 Mar 24;17(3):e1009435
pubmed: 33760811
Nature. 2017 Apr 27;544(7651):503-507
pubmed: 28424523
J Biol Chem. 2020 Jan 3;295(1):146-157
pubmed: 31757807
Am J Hum Genet. 2012 Jun 8;90(6):1014-27
pubmed: 22633399
Cell. 2010 Nov 24;143(5):737-49
pubmed: 21111234
Nat Rev Mol Cell Biol. 2007 May;8(5):379-93
pubmed: 17426725
Nat Cell Biol. 2013 Jan;15(1):40-9
pubmed: 23242214
Mol Biol Cell. 2019 Jan 15;30(2):191-200
pubmed: 30462576
Cell. 2015 Oct 8;163(2):506-19
pubmed: 26451490
Cancer Discov. 2020 Jun;10(6):806-821
pubmed: 32188705
Dev Cell. 2017 Feb 6;40(3):313-322.e5
pubmed: 28132847
Nucleic Acids Res. 2021 Feb 26;49(4):2027-2043
pubmed: 33476374
Nucleic Acids Res. 2008 Nov;36(20):6450-8
pubmed: 18854353
Genome Res. 2002 Aug;12(8):1231-45
pubmed: 12176931
Nat Struct Mol Biol. 2018 Jun;25(6):496-504
pubmed: 29867216
Science. 2003 Oct 10;302(5643):279-82
pubmed: 12970570
Nucleic Acids Res. 2016 Jan 29;44(2):558-72
pubmed: 26420833
J Cell Biol. 2011 Jun 13;193(6):1049-64
pubmed: 21646403
Proc Natl Acad Sci U S A. 2004 Dec 28;101(52):18012-7
pubmed: 15604152