Laminar Necrosis and Hypoxic Damage of the Placenta: A Case-Control Study.


Journal

International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455

Informations de publication

Date de publication:
24 03 2022
Historique:
received: 31 01 2022
revised: 17 03 2022
accepted: 22 03 2022
entrez: 12 4 2022
pubmed: 13 4 2022
medline: 14 4 2022
Statut: epublish

Résumé

The aim of this study is to verify the role of laminar necrosis (LN) in the diagnosis of hypoxic damage of the placenta. This is a retrospective case-control study in which 50 cases with laminar necrosis were compared with 100 gestational age-matched controls without laminar necrosis in a 1:2 ratio. The parameters analyzed were: the presence of other placental lesions, obstetric characteristics and neonatal outcome. For each of the 50 cases, the area affected by the lesion was detected, and the lesions were classified into three groups based on the morphology and time of onset of the lesion in order to understand whether these characteristics of the lesion had a clinical-pathology. The results showed that including the search for LN among placental lesions generally examined is useful to guide the pathologist in the diagnosis of placental dysfunction of hypoxic origin.

Identifiants

pubmed: 35409574
pii: ijerph19073891
doi: 10.3390/ijerph19073891
pmc: PMC8997949
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Katia Mangialardi (K)

Department of Emergency and Organ Transplantation (DETO), Section of Pathology, School of Medicine University of Bari "Aldo Moro", 70124 Bari, Italy.

Margherita Fanelli (M)

Department of Interdisciplinary Medicine, Medical Statistic, School of Medicine University of Bari "Aldo Moro", 70124 Bari, Italy.

Gerardo Cazzato (G)

Department of Emergency and Organ Transplantation (DETO), Section of Pathology, School of Medicine University of Bari "Aldo Moro", 70124 Bari, Italy.

Andrea Marzullo (A)

Department of Emergency and Organ Transplantation (DETO), Section of Pathology, School of Medicine University of Bari "Aldo Moro", 70124 Bari, Italy.

Maria Elisabetta Baldassarre (ME)

Department of Biomedical Sciences and Human Oncology, Neonatology and Neonatal Intensive Care Unit, School of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.

Antonella Vimercati (A)

Department of Biomedical Sciences and Human Oncology, Gynecologic and Obstetrics Clinic, School of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.

Leonardo Resta (L)

Department of Emergency and Organ Transplantation (DETO), Section of Pathology, School of Medicine University of Bari "Aldo Moro", 70124 Bari, Italy.

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