Low lymphocyte count: A clinical severity marker in infants with bronchiolitis.
RSV
bronchiolitis
clinical severity marker
lymphocyte count
oxygen supplementation
Journal
Pediatric pulmonology
ISSN: 1099-0496
Titre abrégé: Pediatr Pulmonol
Pays: United States
ID NLM: 8510590
Informations de publication
Date de publication:
07 2022
07 2022
Historique:
revised:
29
03
2022
received:
17
08
2021
accepted:
31
03
2022
pubmed:
13
4
2022
medline:
25
6
2022
entrez:
12
4
2022
Statut:
ppublish
Résumé
Bronchiolitis is the most frequent cause of hospitalization in infants younger than 1 year of age. We sought to evaluate the correlation between lymphocyte count and clinical manifestation in infants hospitalized with bronchiolitis. We performed a retrospective cohort study evaluating 1297 children hospitalized for bronchiolitis from 2004 to 2019. A nasal washing was tested for 14 respiratory viruses by PCR. A clinical severity score, ranging 0-8, was assigned at hospital admission. History and clinical course were recorded for each infant. Patients were divided in 3 groups according to lymphocyte count tertiles. Parents of enrolled patients have been phoned annually over 5 years to evaluate respiratory sequelae. A total of 433 children had 2914.2 ± 745.5/mm Infants with low lymphocyte count are more likely to have a worse clinical course of bronchiolitis.
Sections du résumé
BACKGROUND
Bronchiolitis is the most frequent cause of hospitalization in infants younger than 1 year of age. We sought to evaluate the correlation between lymphocyte count and clinical manifestation in infants hospitalized with bronchiolitis.
MATERIALS AND METHODS
We performed a retrospective cohort study evaluating 1297 children hospitalized for bronchiolitis from 2004 to 2019. A nasal washing was tested for 14 respiratory viruses by PCR. A clinical severity score, ranging 0-8, was assigned at hospital admission. History and clinical course were recorded for each infant. Patients were divided in 3 groups according to lymphocyte count tertiles. Parents of enrolled patients have been phoned annually over 5 years to evaluate respiratory sequelae.
RESULTS
A total of 433 children had 2914.2 ± 745.5/mm
CONCLUSIONS
Infants with low lymphocyte count are more likely to have a worse clinical course of bronchiolitis.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1770-1775Informations de copyright
© 2022 Wiley Periodicals LLC.
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