Measurement of erythrocyte membrane mannoses to assess splenic function.
glycosylation
membrane editing
oxidative damage
red blood cells
splenectomy
Journal
British journal of haematology
ISSN: 1365-2141
Titre abrégé: Br J Haematol
Pays: England
ID NLM: 0372544
Informations de publication
Date de publication:
07 2022
07 2022
Historique:
revised:
25
02
2022
received:
22
10
2021
accepted:
13
03
2022
pubmed:
13
4
2022
medline:
28
6
2022
entrez:
12
4
2022
Statut:
ppublish
Résumé
Red blood cells (RBCs) lose plasma membrane in the spleen as they age, but the cells and molecules involved are yet to be identified. Sickle cell disease and infection by Plasmodium falciparum cause oxidative stress that induces aggregates of cross-linked proteins with N-linked high-mannose glycans (HMGs). These glycans can be recognised by mannose-binding lectins, including the mannose receptor (CD206), expressed on macrophages and specialised phagocytic endothelial cells in the spleen to mediate the extravascular haemolysis characteristic of these diseases. We postulated this system might also mediate removal of molecules and membrane in healthy individuals. Surface expression of HMGs on RBCs from patients who had previously undergone splenectomy was therefore assessed: high levels were indeed observable as large membrane aggregates. Glycomic analysis by mass spectrometry identified a mixture of Man
Identifiants
pubmed: 35411940
doi: 10.1111/bjh.18164
pmc: PMC9321840
doi:
Substances chimiques
Polysaccharides
0
Mannose
PHA4727WTP
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
155-164Informations de copyright
© 2022 The Authors. British Journal of Haematology published by British Society for Haematology and John Wiley & Sons Ltd.
Références
Blood Adv. 2018 Jan 03;2(1):14-24
pubmed: 29344581
Glycobiology. 2006 May;16(5):422-30
pubmed: 16423983
Br J Haematol. 2022 Jul;198(1):155-164
pubmed: 35411940
Blood. 2015 Oct 8;126(15):1831-4
pubmed: 26276668
Blood. 2020 Oct 1;136(14):1569-1570
pubmed: 33002125
Br J Haematol. 1992 Sep;82(1):126-32
pubmed: 1419786
Am J Hematol. 2016 Sep;91(9):875-82
pubmed: 27194638
Redox Biol. 2014;2:99-104
pubmed: 25460724
Cell Mol Biol (Noisy-le-grand). 2004 Mar;50(2):107-16
pubmed: 15095782
Trends Cell Biol. 2012 Aug;22(8):407-17
pubmed: 22748206
Front Physiol. 2021 Mar 15;12:655393
pubmed: 33790808
Microbiol Spectr. 2016 Oct;4(5):
pubmed: 27780012
Am J Hematol. 1993 Jan;42(1):46-52
pubmed: 8416296
Nat Commun. 2021 Mar 19;12(1):1792
pubmed: 33741926
Glycobiology. 2019 Aug 20;29(9):620-624
pubmed: 31184695
Sci Rep. 2016 Oct 13;6:35234
pubmed: 27734926
Methods Mol Biol. 2012;832:455-61
pubmed: 22350905
J Biol Chem. 2002 Nov 1;277(44):41613-23
pubmed: 12196537
Sci Rep. 2020 Aug 26;10(1):14218
pubmed: 32848178
Biochim Biophys Acta. 2012 Apr;1818(4):1108-14
pubmed: 22100602
Blood. 1959 Apr;14(4):399-408
pubmed: 13638340
Science. 2017 Aug 4;357(6350):
pubmed: 28774900
J Proteome Res. 2008 Apr;7(4):1650-9
pubmed: 18311910
FASEB J. 2006 Apr;20(6):741-3
pubmed: 16469848
Front Physiol. 2013 Dec 25;4:387
pubmed: 24399969
Essays Biochem. 2016 Oct 15;60(2):173-180
pubmed: 27744333
Biochimie. 1998 Feb;80(2):173-95
pubmed: 9587675
J Biol Chem. 1988 Jan 15;263(2):728-34
pubmed: 3335522
Antioxidants (Basel). 2021 Feb 16;10(2):
pubmed: 33669171
Dig Dis. 2022;40(3):290-298
pubmed: 34034254
Prog Mol Biol Transl Sci. 2012;109:227-48
pubmed: 22727423
J Leukoc Biol. 2012 Dec;92(6):1177-86
pubmed: 22966131
Nat Rev Nephrol. 2019 Jun;15(6):346-366
pubmed: 30858582
Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):9574-9579
pubmed: 30190436
Lab Invest. 2005 Oct;85(10):1238-49
pubmed: 16056240
Methods Enzymol. 2006;415:59-86
pubmed: 17116468
Rinsho Ketsueki. 2014 Jun;55(6):607-32
pubmed: 24975331
Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7804-9
pubmed: 27354532
Nat Rev Immunol. 2005 Aug;5(8):606-16
pubmed: 16056254
BMJ. 2019 Jul 4;366:l4183
pubmed: 31272949
BMC Biol. 2017 Jun 29;15(1):53
pubmed: 28662662
Arch Dis Child. 1982 May;57(5):338-42
pubmed: 7092288
Front Physiol. 2018 Nov 16;9:1607
pubmed: 30505281
Front Physiol. 2014 Jan 30;5:9
pubmed: 24523696
Bone Marrow Transplant. 2015 Oct;50(10):1343-7
pubmed: 26168071
Front Immunol. 2017 Feb 02;8:73
pubmed: 28210260
Free Radic Res. 2021 May;55(5):562-580
pubmed: 33427524