The effects of developmental trauma on theory of mind and its relationship to psychotic experiences: A behavioural study.

Adult Female Humans Male Psychotic Disorders / psychology Self Report Theory of Mind
Mentalization Psychiatry Psychopathology Psychosis Schizophrenia Trauma

Journal

Psychiatry research
ISSN: 1872-7123
Titre abrégé: Psychiatry Res
Pays: Ireland
ID NLM: 7911385

Informations de publication

Date de publication:
06 2022
Historique:
received: 12 12 2021
revised: 30 03 2022
accepted: 03 04 2022
pubmed: 14 4 2022
medline: 20 5 2022
entrez: 13 4 2022
Statut: ppublish

Résumé

Developmental psychological trauma induces vulnerability to psychosis. However, the mechanisms underlying this association are poorly understood. Impairments in Theory of Mind (ToM) have been observed in adult survivors of developmental trauma and individuals with psychosis. ToM is therefore a candidate mechanism underlying the association between developmental trauma and psychosis. We used a computerised version of the Director task - where a participant is instructed by a confederate to move an object around a 4 × 4 grid, whilst taking account of whether these objects are visible to a confederate who instructs the participant - to investigate impairments in ToM in 209 participants (age: M = 37.8, SD=13.6; 56% female). Participants were divided into a) developmental trauma-positive (DT+) and control groups (DT-) based on their history of developmental trauma and b) then further into subclinical (S) and healthy groups (H) as based on psychotic experiences indexed by the CAPE-P15. After exclusion, the numbers in each group were: DT+H (47), DT+S (84), DT-H (54), DT-S (12). (Total: 197). Developmental trauma exposure was associated with psychotic experiences (OR: 7.89, p < .001), which remained significant after controlling for demographic and clinical confounds (adjusted R ToM deficits are associated with self-reported developmental trauma and psychotic experiences. Further work is needed to explore these relationships further and whether they represent generalised or specific effect effects on developmental trauma and psychopathological domains.

Sections du résumé

BACKGROUND
Developmental psychological trauma induces vulnerability to psychosis. However, the mechanisms underlying this association are poorly understood. Impairments in Theory of Mind (ToM) have been observed in adult survivors of developmental trauma and individuals with psychosis. ToM is therefore a candidate mechanism underlying the association between developmental trauma and psychosis.
METHODS
We used a computerised version of the Director task - where a participant is instructed by a confederate to move an object around a 4 × 4 grid, whilst taking account of whether these objects are visible to a confederate who instructs the participant - to investigate impairments in ToM in 209 participants (age: M = 37.8, SD=13.6; 56% female). Participants were divided into a) developmental trauma-positive (DT+) and control groups (DT-) based on their history of developmental trauma and b) then further into subclinical (S) and healthy groups (H) as based on psychotic experiences indexed by the CAPE-P15. After exclusion, the numbers in each group were: DT+H (47), DT+S (84), DT-H (54), DT-S (12). (Total: 197).
RESULTS
Developmental trauma exposure was associated with psychotic experiences (OR: 7.89, p < .001), which remained significant after controlling for demographic and clinical confounds (adjusted R
CONCLUSIONS
ToM deficits are associated with self-reported developmental trauma and psychotic experiences. Further work is needed to explore these relationships further and whether they represent generalised or specific effect effects on developmental trauma and psychopathological domains.

Identifiants

DOI: 10.1016/j.psychres.2022.114544 PMID: 35417825
pubmed: 35417825
pii: S0165-1781(22)00155-X
doi: 10.1016/j.psychres.2022.114544
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

114544

Informations de copyright

Copyright © 2022 The Authors. Published by Elsevier B.V. All rights reserved.

Auteurs

Ryan Turner (R)

Translational Psychiatry Research Group, Research Department of Mental Health Neuroscience, Division of Psychiatry, UCL Institute of Mental Health, University College London, Wing A, 6th floor, Maple House, 149 Tottenham Court Road, London, W1T 7NF United Kingdom. Electronic address: ryan.turner.18@ucl.ac.uk.

Krisya Louie (K)

Translational Psychiatry Research Group, Research Department of Mental Health Neuroscience, Division of Psychiatry, UCL Institute of Mental Health, University College London, Wing A, 6th floor, Maple House, 149 Tottenham Court Road, London, W1T 7NF United Kingdom. Electronic address: krisya@connect.hku.hk.

Ameerah Parvez (A)

Translational Psychiatry Research Group, Research Department of Mental Health Neuroscience, Division of Psychiatry, UCL Institute of Mental Health, University College London, Wing A, 6th floor, Maple House, 149 Tottenham Court Road, London, W1T 7NF United Kingdom. Electronic address: ameerah.parvez.18@ucl.ac.uk.

Mustapha Modaffar (M)

Translational Psychiatry Research Group, Research Department of Mental Health Neuroscience, Division of Psychiatry, UCL Institute of Mental Health, University College London, Wing A, 6th floor, Maple House, 149 Tottenham Court Road, London, W1T 7NF United Kingdom. Electronic address: mustapha.modaffar.15@alumni.ucl.ac.uk.

Rowan Rezaie (R)

Translational Psychiatry Research Group, Research Department of Mental Health Neuroscience, Division of Psychiatry, UCL Institute of Mental Health, University College London, Wing A, 6th floor, Maple House, 149 Tottenham Court Road, London, W1T 7NF United Kingdom. Electronic address: rowan.rezaie.17@ucl.ac.uk.

Talya Greene (T)

Translational Psychiatry Research Group, Research Department of Mental Health Neuroscience, Division of Psychiatry, UCL Institute of Mental Health, University College London, Wing A, 6th floor, Maple House, 149 Tottenham Court Road, London, W1T 7NF United Kingdom. Electronic address: tgreene@univ.haifa.ac.il.

James Bisby (J)

Translational Psychiatry Research Group, Research Department of Mental Health Neuroscience, Division of Psychiatry, UCL Institute of Mental Health, University College London, Wing A, 6th floor, Maple House, 149 Tottenham Court Road, London, W1T 7NF United Kingdom. Electronic address: j.bisby@ucl.ac.uk.

Peter Fonagy (P)

Psychoanalysis Unit, Research Department of Clinical, Educational and Health Psychology, University College London, Gower Street, London, WC1E 6BT United Kingdom. Electronic address: p.fonagy@ucl.ac.uk.

Michael A P Bloomfield (MAP)

Translational Psychiatry Research Group, Research Department of Mental Health Neuroscience, Division of Psychiatry, UCL Institute of Mental Health, University College London, Wing A, 6th floor, Maple House, 149 Tottenham Court Road, London, W1T 7NF United Kingdom; Clinical Psychopharmacology Unit, Research Department of Clinical, Educational and Health Psychology, University College London, Gower Street, London WC1E 7HB, United Kingdom; NIHR University College London Hospitals Biomedical Research Centre, Research & Development, University College Hospital, Maple House Suite A 1st Floor, 149 Tottenham Court Road, London, W1T 7DN United Kingdom; Psychiatric Imaging Group, MRC London Institute of Medical Sciences, Hammersmith Hospital Campus, Imperial College London, W12 0NN United Kingdom; The Traumatic Stress Clinic, St Pancras Hospital, Camden & Islington NHS Foundation Trust, 4St Pancras Way, London, NW1 0PE United Kingdom; National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, Queen Square, London, WC1N 3BG United Kingdom. Electronic address: m.bloomfield@ucl.ac.uk.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › The effects of developmental trauma on theory...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The effects of developmental trauma on theory...
questionsmedicales.fr › Troubles mentaux › Schizophrénie et troubles avec traits psychotiques › Troubles psychotiques › The effects of developmental trauma on theory...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Enquêtes et questionnaires › Autorapport › The effects of developmental trauma on theory...
questionsmedicales.fr › Phénomènes psychologiques › Théorie psychologique › Théorie de l'esprit › The effects of developmental trauma on theory...