Mapping human haematopoietic stem cells from haemogenic endothelium to birth.

Cell Differentiation Endothelial Cells Endothelium Female Hematopoiesis Hematopoietic Stem Cells Humans Mesonephros Pregnancy

Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
04 2022
Historique:
received: 31 12 2020
accepted: 22 02 2022
pubmed: 15 4 2022
medline: 23 4 2022
entrez: 14 4 2022
Statut: ppublish

Résumé

The ontogeny of human haematopoietic stem cells (HSCs) is poorly defined owing to the inability to identify HSCs as they emerge and mature at different haematopoietic sites

Identifiants

DOI: 10.1038/s41586-022-04571-x PMID: 35418685 PMC: PMC9645817
pubmed: 35418685
doi: 10.1038/s41586-022-04571-x
pii: 10.1038/s41586-022-04571-x
pmc: PMC9645817
mid: NIHMS1808640
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

534-540

Subventions

Organisme : NHLBI NIH HHS
ID : R01 HL148714
Pays : United States
Organisme : NHLBI NIH HHS
ID : R35 HL140014
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL086345
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK100959
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL069766
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK125097
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK121557
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA016042
Pays : United States
Organisme : NIAID NIH HHS
ID : P30 AI028697
Pays : United States

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer Nature Limited.

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Auteurs

Vincenzo Calvanese (V)

Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA. v.calvanese@ucl.ac.uk.
Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, USA. v.calvanese@ucl.ac.uk.
Laboratory for Molecular Cell Biology, University College London, London, UK. v.calvanese@ucl.ac.uk.
ORCID: 0000-0002-7937-1511

Sandra Capellera-Garcia (S)

Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.
Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, USA.

Feiyang Ma (F)

Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.
Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, USA.
Chongqing International Institute for Immunology, Chongqing, China.
ORCID: 0000-0002-6260-0787

Iman Fares (I)

Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.
Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, USA.

Simone Liebscher (S)

Institute of Biomedical Engineering, Department for Medical Technologies and Regenerative Medicine, Eberhard Karls University, Tübingen, Germany.

Elizabeth S Ng (ES)

Murdoch Children's Research Institute, The Royal Children's Hospital, Parkville, Victoria, Australia.

Sophia Ekstrand (S)

Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.
Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, USA.

Júlia Aguadé-Gorgorió (J)

Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.
Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, USA.
ORCID: 0000-0001-5600-4279

Anastasia Vavilina (A)

Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.
Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, USA.

Diane Lefaudeux (D)

Signaling Systems Laboratory, Department of Microbiology Immunology and Molecular Genetics (MIMG), University of California Los Angeles, Los Angeles, CA, USA.
Institute for Quantitative and Computational Biosciences (QCB), University of California Los Angeles, Los Angeles, CA, USA.

Brian Nadel (B)

Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.
ORCID: 0000-0002-9583-8169

Jacky Y Li (JY)

Murdoch Children's Research Institute, The Royal Children's Hospital, Parkville, Victoria, Australia.

Yanling Wang (Y)

Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.

Lydia K Lee (LK)

Department of Obstetrics and Gynecology, University of California Los Angeles, Los Angeles, CA, USA.

Reza Ardehali (R)

Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, USA.
Department of Medicine/Cardiology, CVRL, University of California Los Angeles, Los Angeles, CA, USA.
ORCID: 0000-0003-1318-4016

M Luisa Iruela-Arispe (ML)

Cell and Developmental Biology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.
ORCID: 0000-0002-3050-4168

Matteo Pellegrini (M)

Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.
Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, USA.

Ed G Stanley (EG)

Murdoch Children's Research Institute, The Royal Children's Hospital, Parkville, Victoria, Australia.
Department of Paediatrics, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Victoria, Australia.
Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.

Andrew G Elefanty (AG)

Murdoch Children's Research Institute, The Royal Children's Hospital, Parkville, Victoria, Australia.
Department of Paediatrics, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Victoria, Australia.
Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.
ORCID: 0000-0001-6448-8314

Katja Schenke-Layland (K)

Institute of Biomedical Engineering, Department for Medical Technologies and Regenerative Medicine, Eberhard Karls University, Tübingen, Germany.
Department of Medicine/Cardiology, CVRL, University of California Los Angeles, Los Angeles, CA, USA.
Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls University Tübingen, Tübingen, Germany.
NMI Natural and Medical Sciences Institute, University Tübingen, Reutlingen, Germany.
ORCID: 0000-0001-8066-5157

Hanna K A Mikkola (HKA)

Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA. hmikkola@mcdb.ucla.edu.
Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, USA. hmikkola@mcdb.ucla.edu.
ORCID: 0000-0002-3400-1496

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Classifications MeSH

questionsmedicales.fr › Phénomènes physiologiques cellulaires › Différenciation cellulaire › Mapping human haematopoietic stem cells from...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules endothéliales › Mapping human haematopoietic stem cells from...
questionsmedicales.fr › Tissus › Épithélium › Endothélium › Mapping human haematopoietic stem cells from...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiogiques du sang › Hématopoïèse › Mapping human haematopoietic stem cells from...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système hématopoïétique › Cellules de la moelle osseuse › Cellules souches hématopoïétiques › Mapping human haematopoietic stem cells from...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Mapping human haematopoietic stem cells from...
questionsmedicales.fr › Structures de l'embryon › Mésonéphros › Mapping human haematopoietic stem cells from...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Mapping human haematopoietic stem cells from...