Fenofibrate, which reduces risk of sight-threatening diabetic retinopathy in type 2 diabetes, is associated with early narrowing of retinal venules: a FIELD trial substudy.
diabetes
diabetic retinopathy
microvascular complication
retinal grading
Journal
Internal medicine journal
ISSN: 1445-5994
Titre abrégé: Intern Med J
Pays: Australia
ID NLM: 101092952
Informations de publication
Date de publication:
04 2022
04 2022
Historique:
revised:
04
12
2021
received:
15
09
2021
accepted:
06
12
2021
entrez:
14
4
2022
pubmed:
15
4
2022
medline:
16
4
2022
Statut:
ppublish
Résumé
Retinal vessel calibre metrics were evaluated at baseline and 2 years in a FIELD substudy (n = 208). Central retinal venule calibre was significantly reduced by fenofibrate and unchanged by placebo. Arteriole metrics did not change. Larger studies relating retinal vessel calibre to future diabetes complications and response to therapy are merited.
Substances chimiques
Fenofibrate
U202363UOS
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
676-679Subventions
Organisme : Laboratoires Fournier
Organisme : National Health and Medical Research Council
Organisme : National Heart Foundation of Australia
Informations de copyright
© 2022 Royal Australasian College of Physicians.
Références
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