Design and property investigation on a five-interaction-based fluorescent anion receptor clip.
Journal
RSC advances
ISSN: 2046-2069
Titre abrégé: RSC Adv
Pays: England
ID NLM: 101581657
Informations de publication
Date de publication:
01 Mar 2021
01 Mar 2021
Historique:
received:
24
01
2021
accepted:
23
02
2021
entrez:
15
4
2022
pubmed:
16
4
2022
medline:
16
4
2022
Statut:
epublish
Résumé
A molecular clip combining a doubly substituted fluorescent anion-π donor probe and two flexible arms bearing H-bond motifs constitutes a new generation of anion receptors. Five simultaneous non-covalent interactions are highlighted by theoretical complexation studies with five different anions. A large range of analytical techniques (electrospray-tandem mass spectrometry, NMR, UV-visible, steady-state and time-resolved fluorescence) were deployed to evaluate the stoichiometry and association constants with the selected anions. The photophysical and anion-π donor properties of the tetrazine ring allowed fine characterization of the binding properties of the ligand. Based on previously published results, an anti-cooperativity effect in non-covalent interactions was demonstrated.
Identifiants
pubmed: 35423419
doi: 10.1039/d1ra00630d
pii: d1ra00630d
pmc: PMC8695457
doi:
Types de publication
Journal Article
Langues
eng
Pagination
9476-9487Informations de copyright
This journal is © The Royal Society of Chemistry.
Déclaration de conflit d'intérêts
There are no conflicts to declare.
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