Synthesis of benzoin under supramolecular catalysis involving cyclodextrins in water: application for the preparation of the antiepileptic drug phenytoin.


Journal

RSC advances
ISSN: 2046-2069
Titre abrégé: RSC Adv
Pays: England
ID NLM: 101581657

Informations de publication

Date de publication:
31 Mar 2022
Historique:
received: 15 12 2021
accepted: 23 03 2022
entrez: 15 4 2022
pubmed: 16 4 2022
medline: 16 4 2022
Statut: epublish

Résumé

Among the cyclodextrins screened for the synthesis of 2-hydroxy-1,2-diphenylethanone (benzoin) in water, 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) exhibited the highest yield in the benzoin condensation reactions, and HP-β-CD can be recycled several times with little loss of activity through the addition of fresh VB

Identifiants

pubmed: 35424977
doi: 10.1039/d1ra09062c
pii: d1ra09062c
pmc: PMC8978206
doi:

Types de publication

Journal Article

Langues

eng

Pagination

10460-10466

Informations de copyright

This journal is © The Royal Society of Chemistry.

Déclaration de conflit d'intérêts

There are no conflicts to declare.

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Auteurs

Zhichao Jin (Z)

School of Pharmacy, Ningxia Medical University Yinchuan 750004 China qinghuang1982@163.com wangzzsc@163.com.

Chunhua Yan (C)

School of Pharmacy, Ningxia Medical University Yinchuan 750004 China qinghuang1982@163.com wangzzsc@163.com.

Huimin Chu (H)

School of Pharmacy, Ningxia Medical University Yinchuan 750004 China qinghuang1982@163.com wangzzsc@163.com.

Qing Huang (Q)

School of Pharmacy, Ningxia Medical University Yinchuan 750004 China qinghuang1982@163.com wangzzsc@163.com.
Key Laboratory of Ningxia Ethnomedicine Modernization, Ministry of Education Yinchuan 750004 China.

Zhizhong Wang (Z)

School of Pharmacy, Ningxia Medical University Yinchuan 750004 China qinghuang1982@163.com wangzzsc@163.com.
Key Laboratory of Ningxia Ethnomedicine Modernization, Ministry of Education Yinchuan 750004 China.

Classifications MeSH