The peculiar dermatoscopic pattern of scalp melanoma.


Journal

Journal of the European Academy of Dermatology and Venereology : JEADV
ISSN: 1468-3083
Titre abrégé: J Eur Acad Dermatol Venereol
Pays: England
ID NLM: 9216037

Informations de publication

Date de publication:
Sep 2022
Historique:
revised: 11 03 2022
received: 25 01 2022
accepted: 24 03 2022
pubmed: 16 4 2022
medline: 23 8 2022
entrez: 15 4 2022
Statut: ppublish

Résumé

Melanomas developing on anatomic sites other than the trunk and extremities have a special pathogenetic and mutational profile, morphologic characteristics and biologic behaviour. By retrospectively screening the databases of our centres, we aimed to investigate the dermatoscopic morphology of early scalp melanoma, including in situ and invasive tumours with a Breslow thickness up to 1 mm. The databases of three specialized centres for skin cancer diagnosis and management in Greece were retrospectively evaluated to retrieve dermatoscopic images of scalp melanomas. Patients' age and sex were recorded, as well as the precise location of the tumour, using 6 possible sub-locations: frontal, parietal, occipital, temporal, nuchal scalp and vertex. The dermatoscopic images were evaluated by 3 independent investigators for the presence of pre-defined criteria. The dermatoscopic criteria included in the evaluation were selected based on available literature and were categorized in 2 groups: 'classic melanoma criteria' and 'lentigo maligna (LM) criteria'. Of 38 melanomas, 37 (97.4%) displayed brown colour and 23 (60.5%) displayed additional grey or blue colour. The most frequent dermatoscopic criteria were regression (18/38, 47.4%), grey dots/globules (17/38, 44.7%), atypical network (16/38, 42.1%), obliterated follicles (16/38, 42.1%) and angulated lines (15/38, 39.5%). Of 38 melanomas, 28 (73.7%) displayed at least 1 classic melanoma criterion plus at least 1 LM criterion. Of the remaining melanomas, 8 (21.1%) displayed only classic melanoma criteria, 1 (2.6%) only LM criteria and 1 (2.6%) did not exhibit any of the evaluated criteria. This study demonstrates that early scalp melanoma combines classic with LM criteria in terms of colours and structures.

Sections du résumé

BACKGROUND BACKGROUND
Melanomas developing on anatomic sites other than the trunk and extremities have a special pathogenetic and mutational profile, morphologic characteristics and biologic behaviour.
OBJECTIVE OBJECTIVE
By retrospectively screening the databases of our centres, we aimed to investigate the dermatoscopic morphology of early scalp melanoma, including in situ and invasive tumours with a Breslow thickness up to 1 mm.
METHODS METHODS
The databases of three specialized centres for skin cancer diagnosis and management in Greece were retrospectively evaluated to retrieve dermatoscopic images of scalp melanomas. Patients' age and sex were recorded, as well as the precise location of the tumour, using 6 possible sub-locations: frontal, parietal, occipital, temporal, nuchal scalp and vertex. The dermatoscopic images were evaluated by 3 independent investigators for the presence of pre-defined criteria. The dermatoscopic criteria included in the evaluation were selected based on available literature and were categorized in 2 groups: 'classic melanoma criteria' and 'lentigo maligna (LM) criteria'.
RESULTS RESULTS
Of 38 melanomas, 37 (97.4%) displayed brown colour and 23 (60.5%) displayed additional grey or blue colour. The most frequent dermatoscopic criteria were regression (18/38, 47.4%), grey dots/globules (17/38, 44.7%), atypical network (16/38, 42.1%), obliterated follicles (16/38, 42.1%) and angulated lines (15/38, 39.5%). Of 38 melanomas, 28 (73.7%) displayed at least 1 classic melanoma criterion plus at least 1 LM criterion. Of the remaining melanomas, 8 (21.1%) displayed only classic melanoma criteria, 1 (2.6%) only LM criteria and 1 (2.6%) did not exhibit any of the evaluated criteria.
CONCLUSIONS CONCLUSIONS
This study demonstrates that early scalp melanoma combines classic with LM criteria in terms of colours and structures.

Identifiants

pubmed: 35426175
doi: 10.1111/jdv.18145
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1564-1567

Informations de copyright

© 2022 European Academy of Dermatology and Venereology.

Références

Ozao-Choy J, Nelson DW, Hiles J et al. The prognostic importance of scalp location in primary head and neck melanoma. J Surg Oncol 2017; 116: 337-343.
Lachiewicz AM, Berwick M, Wiggins CL, Thomas NE. Survival differences between patients with scalp or neck melanoma and those with melanoma of other sites in the surveillance, epidemiology, and end results (SEER) program. Arch Dermatol 2008; 144: 515-521.
Tseng WH, Martinez SR. Tumor location predicts survival in cutaneous head and neck melanoma. J Surg Res 2011; 167: 192-198.
Lallas A, Argenziano G, Zendri E et al. Update on non-melanoma skin cancer and the value of dermoscopy in its diagnosis and treatment monitoring. Expert Rev Anticancer Ther 2013; 13: 541-558.
Benati E, Longo C, Bombonato C, Moscarella E, Alfano R, Argenziano G. Baldness and scalp melanoma. J Eur Acad Dermatol Venereol 2017; 31: e528-e530.
Stanganelli I, Argenziano G, Sera F et al. Dermoscopy of scalp tumours: a multi-Centre study conducted by the international dermoscopy society. J Eur Acad Dermatol Venereol 2012; 26: 953-963.
Chamberlain AJ, Fritschi L, Giles GG et al. Nodular type and older age as the most significant associations of thick melanoma inVictoria. Aust Arch Dermatol 2002; 138: 609-614.
Tejera-Vaquerizo A, Solis-Garcia E, Moreno-Ramirez D et al. Primary cutaneous melanoma: prognostic factors not included in the classification of the American joint committee on cancer. Actas Dermosifiliogr 2011; 102: 255-263.

Auteurs

I Spyridis (I)

First Dermatology Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.

C Papageorgiou (C)

Second Dermatology Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Z Apalla (Z)

Second Dermatology Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.

S M Manoli (SM)

First Dermatology Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.

P Eftychidoy (P)

First Dermatology Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.

T Gkentsidi (T)

First Dermatology Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.

M Bobos (M)

First Dermatology Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Department of Biomedical Science, School of Health Sciences, International Hellenic University, Thessaloniki, Greece.

A Boutis (A)

First Dermatology Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.
First Department of Medical Oncology, Theageneio Cancer Hospital, Thessaloniki, Greece.

E Vakirlis (E)

First Dermatology Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.

E Sotiriou (E)

First Dermatology Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.

D Ioannides (D)

First Dermatology Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.

A Lallas (A)

First Dermatology Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.

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