Effect of an acute exercise on early responses of iron and iron regulatory proteins in young female basketball players.
Acute exercise
Female athletes
Ferritin
Hepcidin
IL-6
Iron homeostasis
Transferrin
Journal
BMC sports science, medicine & rehabilitation
ISSN: 2052-1847
Titre abrégé: BMC Sports Sci Med Rehabil
Pays: England
ID NLM: 101605016
Informations de publication
Date de publication:
15 Apr 2022
15 Apr 2022
Historique:
received:
15
02
2022
accepted:
07
04
2022
entrez:
16
4
2022
pubmed:
17
4
2022
medline:
17
4
2022
Statut:
epublish
Résumé
The accumulation of physiological stress and the presence of inflammation disturb iron management in athletes during intense training. However, little is known about the mechanisms regulating iron levels in athletes during training periods with low training loads. In the current study, we analyzed the effect of an acute exercise on early responses of iron and iron regulatory proteins at the end of such training periods. The study was performed at the end of competitive phase of training. A total of 27 trained female basketball players were included in the study after application of the inclusion/exclusion criteria. The participants performed an incremental exercise on a treadmill. Blood samples were taken before the test, immediately after exercise, and after 3 h of restitution. Parameters, such as interleukin (IL) 6, hepcidin, ferritin, transferrin, hemopexin, and lactoferrin levels, total iron-biding capacity (TIBC), unsaturated iron-biding capacity (UIBC) were determined by using appropriate biochemical tests. The level of iron increased significantly after exercise, and then decreased within next 3 h restitution. Except for iron levels, only TIBC levels significantly increased after exercise and decreased to baseline level during rest period. No significant changes in the levels of hepcidin, IL-6, and other proteins related to the iron homeostasis were observed. The increases in iron level after acute exercise is short-term and transient and appear to have been insufficient to induce the acute systemic effects in rested athletes.
Sections du résumé
BACKGROUND
BACKGROUND
The accumulation of physiological stress and the presence of inflammation disturb iron management in athletes during intense training. However, little is known about the mechanisms regulating iron levels in athletes during training periods with low training loads. In the current study, we analyzed the effect of an acute exercise on early responses of iron and iron regulatory proteins at the end of such training periods.
METHODS
METHODS
The study was performed at the end of competitive phase of training. A total of 27 trained female basketball players were included in the study after application of the inclusion/exclusion criteria. The participants performed an incremental exercise on a treadmill. Blood samples were taken before the test, immediately after exercise, and after 3 h of restitution. Parameters, such as interleukin (IL) 6, hepcidin, ferritin, transferrin, hemopexin, and lactoferrin levels, total iron-biding capacity (TIBC), unsaturated iron-biding capacity (UIBC) were determined by using appropriate biochemical tests.
RESULTS
RESULTS
The level of iron increased significantly after exercise, and then decreased within next 3 h restitution. Except for iron levels, only TIBC levels significantly increased after exercise and decreased to baseline level during rest period. No significant changes in the levels of hepcidin, IL-6, and other proteins related to the iron homeostasis were observed.
CONCLUSIONS
CONCLUSIONS
The increases in iron level after acute exercise is short-term and transient and appear to have been insufficient to induce the acute systemic effects in rested athletes.
Identifiants
pubmed: 35428332
doi: 10.1186/s13102-022-00465-7
pii: 10.1186/s13102-022-00465-7
pmc: PMC9013050
doi:
Types de publication
Journal Article
Langues
eng
Pagination
69Informations de copyright
© 2022. The Author(s).
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