Water-soluble anionic polychloramide biocides based on maleic anhydride copolymers.
Antimicrobial polymers
Cellulose grafting
Chloramides
Grafted biocide
Journal
Colloids and surfaces. B, Biointerfaces
ISSN: 1873-4367
Titre abrégé: Colloids Surf B Biointerfaces
Pays: Netherlands
ID NLM: 9315133
Informations de publication
Date de publication:
Jul 2022
Jul 2022
Historique:
received:
17
01
2022
revised:
17
03
2022
accepted:
26
03
2022
pubmed:
18
4
2022
medline:
3
6
2022
entrez:
17
4
2022
Statut:
ppublish
Résumé
Our goal was to develop film-forming polymers to extend the antimicrobial lifetimes of cleaned and disinfected surfaces. Antimicrobial polymers were prepared by first reacting poly(ethylene-alt-maleic anhydride) with isopropylamine, partially consuming the anhydride groups, followed by hydrolysis to give water-soluble, highly anionic polyamide PC3. Chlorination with NaOCl gave PC3Cl with oxidative chlorine contents up to 9 wt%. Dried, 5 µm thick, PC3Cl films, gave log 4 reductions in the concentration of Escherichia coli or Staphylococcus aureus exposed to films. A unique feature of the maleic anhydride copolymer platform was the ability to form covalent grafts to surfaces via anhydride reactions. PC3 solution was impregnated into cellulosic filter paper, heated to form ester linkages with cellulose, followed by chlorination with sodium dichloroisocyanurate dihydrate giving grafted PC3Cl. The treated paper (0.3 wt% PC3Cl) gave a log 4 reduction of E. coli concentration in 30 min.
Identifiants
pubmed: 35430484
pii: S0927-7765(22)00170-9
doi: 10.1016/j.colsurfb.2022.112487
pii:
doi:
Substances chimiques
Anti-Infective Agents
0
Disinfectants
0
Maleic Anhydrides
0
Polymers
0
Water
059QF0KO0R
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
112487Informations de copyright
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