Selectivity, Speciation, and Substrate Control in the Gold-Catalyzed Coupling of Indoles and Alkynes.
Journal
Organometallics
ISSN: 0276-7333
Titre abrégé: Organometallics
Pays: United States
ID NLM: 9881295
Informations de publication
Date de publication:
28 Feb 2022
28 Feb 2022
Historique:
received:
19
01
2022
entrez:
18
4
2022
pubmed:
19
4
2022
medline:
19
4
2022
Statut:
ppublish
Résumé
A convenient and mild protocol for the gold-catalyzed intermolecular coupling of substituted indoles with carbonyl-functionalized alkynes to give vinyl indoles is reported. This reaction affords 3-substituted indoles in high yield, and in contrast to the analogous reactions with simple alkynes which give
Identifiants
pubmed: 35431397
doi: 10.1021/acs.organomet.2c00035
pmc: PMC9007570
doi:
Types de publication
Journal Article
Langues
eng
Pagination
497-507Informations de copyright
© 2022 American Chemical Society.
Déclaration de conflit d'intérêts
The authors declare no competing financial interest.
Références
Org Lett. 2014 Nov 7;16(21):5800-3
pubmed: 25341623
Bioorg Med Chem. 2011 Jul 1;19(13):4067-74
pubmed: 21641807
Chemistry. 2007;13(5):1358-73
pubmed: 17206736
Chem Commun (Camb). 2018 Apr 5;54(29):3625-3628
pubmed: 29577155
Chemistry. 2016 Jun 20;22(26):8777-80
pubmed: 27124236
Chem Rev. 2021 Jul 28;121(14):8756-8867
pubmed: 33226774
Chem Commun (Camb). 2017 Jul 6;53(55):7732-7735
pubmed: 28492644
Angew Chem Int Ed Engl. 2016 Aug 8;55(33):9671-5
pubmed: 27435296
Angew Chem Int Ed Engl. 2020 Sep 28;59(40):17739-17749
pubmed: 32515893
Org Lett. 2020 Sep 4;22(17):6977-6981
pubmed: 32845648
J Am Chem Soc. 2017 Jul 19;139(28):9605-9614
pubmed: 28621936
Org Lett. 2022 Jan 21;24(2):668-674
pubmed: 34985297
Chem Commun (Camb). 2015 Jun 14;51(47):9702-5
pubmed: 25978687
Dalton Trans. 2016 Aug 9;45(32):12611-26
pubmed: 27415145
Angew Chem Int Ed Engl. 2015 Jun 22;54(26):7640-3
pubmed: 25960013
J Org Chem. 2011 Nov 18;76(22):9353-61
pubmed: 22010906
Angew Chem Int Ed Engl. 2016 Oct 24;55(44):13798-13802
pubmed: 27689850
Angew Chem Int Ed Engl. 2020 Jun 8;59(24):9433-9437
pubmed: 32078231
Org Lett. 2020 Feb 7;22(3):1175-1181
pubmed: 31940208
Org Lett. 2005 Sep 15;7(19):4133-6
pubmed: 16146370
J Am Chem Soc. 2020 Sep 16;142(37):16082-16089
pubmed: 32813511
Angew Chem Int Ed Engl. 2016 Sep 26;55(40):12455-9
pubmed: 27603008
Chem Commun (Camb). 2019 Dec 3;55(97):14613-14616
pubmed: 31742577
Org Lett. 2021 Mar 19;23(6):2063-2068
pubmed: 33645997
Angew Chem Int Ed Engl. 2005 May 13;44(20):3125-9
pubmed: 15828033
J Org Chem. 2015 Aug 7;80(15):7635-41
pubmed: 26180938
Bioorg Med Chem Lett. 2010 Jul 1;20(13):3916-9
pubmed: 20627724
Bioorg Med Chem Lett. 2010 Feb 1;20(3):824-7
pubmed: 20064720
J Med Chem. 2012 Mar 8;55(5):1940-56
pubmed: 22335538
Org Lett. 2012 Dec 7;14(23):5920-3
pubmed: 23146075
Chem Commun (Camb). 2016 Aug 4;52(60):9422-5
pubmed: 27377712
Chem Rev. 2021 Jul 28;121(14):8452-8477
pubmed: 33476128
Org Lett. 2017 Nov 3;19(21):5848-5851
pubmed: 29058906
Org Lett. 2015 Sep 4;17(17):4372-5
pubmed: 26293968
Chem Sci. 2019 Dec 13;11(5):1353-1360
pubmed: 34123259
J Med Chem. 2011 Aug 11;54(15):5320-34
pubmed: 21726069
J Am Chem Soc. 2009 Mar 11;131(9):3170-1
pubmed: 19219980