Compound Motor Action Potentials During a Modest Nerve Crush.

axonotmesis compound motor action potential (CMAP) controlled compression parameters controlled crush parameters force-impulse instrumented forceps with force transducer nerve crush with feedback rat sciatic tibial nerve crush injury

Journal

Frontiers in cellular neuroscience
ISSN: 1662-5102
Titre abrégé: Front Cell Neurosci
Pays: Switzerland
ID NLM: 101477935

Informations de publication

Date de publication:
2022
Historique:
received: 19 10 2021
accepted: 03 03 2022
entrez: 18 4 2022
pubmed: 19 4 2022
medline: 19 4 2022
Statut: epublish

Résumé

Nerve crush injury results in axonotmesis, characterized by disruption of axons and their myelin sheaths with relative sparing of the nerve's connective tissue. Despite the widespread use of crush injury models, no standardized method for producing these lesions has been established. We characterize a crush model in which a narrow forceps is used to induce a modest and controlled compressive injury. The instantaneous compound motor action potential (CMAP) is monitored

Identifiants

pubmed: 35431816
doi: 10.3389/fncel.2022.798203
pmc: PMC9005805
doi:

Types de publication

Journal Article

Langues

eng

Pagination

798203

Informations de copyright

Copyright © 2022 Hamad, Boroda, Echenique, Dieter, Amirouche, Gonzalez and Kerns.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Mohammed Nazmy Hamad (MN)

Department of Orthopedic Surgery, University of Illinois Chicago, Chicago, IL, United States.

Nickolas Boroda (N)

Department of Orthopedic Surgery, University of Illinois Chicago, Chicago, IL, United States.

Diego Barragan Echenique (DB)

Department of Orthopedic Surgery, University of Illinois Chicago, Chicago, IL, United States.

Raymond A Dieter (RA)

Hines Veterans Affairs Hospital Research Service, Hines, IL, United States.

Farid M L Amirouche (FML)

Department of Orthopedic Surgery, University of Illinois Chicago, Chicago, IL, United States.

Mark H Gonzalez (MH)

Department of Orthopedic Surgery, University of Illinois Chicago, Chicago, IL, United States.

James M Kerns (JM)

Department of Orthopedic Surgery, University of Illinois Chicago, Chicago, IL, United States.

Classifications MeSH