Antisense Peptide Nucleic Acid-Diaminobutanoic Acid Dendron Conjugates with SbmA-Independent Antimicrobial Activity against Gram-Negative Bacteria.
Gram-negative bacteria
PNA
antibiotics
antisense
dendron
Journal
ACS infectious diseases
ISSN: 2373-8227
Titre abrégé: ACS Infect Dis
Pays: United States
ID NLM: 101654580
Informations de publication
Date de publication:
13 05 2022
13 05 2022
Historique:
pubmed:
19
4
2022
medline:
18
5
2022
entrez:
18
4
2022
Statut:
ppublish
Résumé
Precision antisense antibacterial agents may be developed into novel antibiotics in the fight against multidrug-resistant Gram-negative bacteria. In this study, a series of diaminobutanoic acid (DAB) dendrons are presented as novel carriers for the delivery of antisense antibacterial peptide nucleic acids (PNAs). The dendron-PNA conjugates targeting the essential
Identifiants
pubmed: 35436109
doi: 10.1021/acsinfecdis.2c00089
pmc: PMC9112330
doi:
Substances chimiques
Anti-Bacterial Agents
0
Dendrimers
0
Escherichia coli Proteins
0
Membrane Transport Proteins
0
Peptide Nucleic Acids
0
Peptides
0
SbmA protein, E coli
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1098-1106Références
Antimicrob Agents Chemother. 2009 Feb;53(2):525-30
pubmed: 19015356
Biopolymers. 1995;37(2):105-22
pubmed: 7893944
Nucleic Acid Ther. 2012 Oct;22(5):323-34
pubmed: 23030590
Curr Genet. 2022 Feb;68(1):83-90
pubmed: 34750687
Chem Rev. 2021 May 12;121(9):5158-5192
pubmed: 33724823
Nature. 2002 Jan 24;415(6870):389-95
pubmed: 11807545
Bioconjug Chem. 2016 Apr 20;27(4):863-7
pubmed: 26938833
Nat Biotechnol. 2001 Apr;19(4):360-4
pubmed: 11283595
Front Microbiol. 2019 May 24;10:1032
pubmed: 31178830
Nat Protoc. 2008;3(2):163-75
pubmed: 18274517
FEMS Microbiol Lett. 2012 May;330(2):81-9
pubmed: 22339775
Curr Protein Pept Sci. 2005 Feb;6(1):35-51
pubmed: 15638767
Antimicrob Agents Chemother. 2012 Dec;56(12):6147-53
pubmed: 22985881
Lancet. 2022 Feb 12;399(10325):629-655
pubmed: 35065702
Nat Chem Biol. 2020 Dec;16(12):1293-1302
pubmed: 33199906
Biomedicines. 2021 Apr 15;9(4):
pubmed: 33921011
ACS Chem Biol. 2013 Feb 15;8(2):360-7
pubmed: 23138594
Microb Drug Resist. 2014 Aug;20(4):316-24
pubmed: 24517383
Nat Biotechnol. 1998 Apr;16(4):355-8
pubmed: 9555726
Nat Chem Biol. 2013 Apr;9(4):222-31
pubmed: 23508188
Oligonucleotides. 2008 Sep;18(3):277-86
pubmed: 18729823
ACS Chem Biol. 2021 Mar 19;16(3):471-479
pubmed: 33684286
Mol Microbiol. 2007 Oct;66(1):151-63
pubmed: 17725560
Biomacromolecules. 2012 Oct 8;13(10):3127-37
pubmed: 22931162
Appl Microbiol Biotechnol. 2018 Feb;102(3):1055-1065
pubmed: 29209794
Nat Rev Chem. 2021;5(10):726-749
pubmed: 34426795
Expert Opin Drug Saf. 2015;14(11):1687-701
pubmed: 26365594
Antisense Nucleic Acid Drug Dev. 2002 Apr;12(2):65-70
pubmed: 12074366
Nat Biotechnol. 2006 Dec;24(12):1551-7
pubmed: 17160061
Pharmacol Rev. 2003 Mar;55(1):27-55
pubmed: 12615953
Mol Ther Nucleic Acids. 2021 Jun 24;25:444-454
pubmed: 34484867
Nucleic Acid Ther. 2021 Jun;31(3):208-219
pubmed: 32678992
Biomacromolecules. 2020 Feb 10;21(2):472-483
pubmed: 31756087
FEMS Microbiol Lett. 2010 Oct;311(2):185-92
pubmed: 20735480
Protein Pept Lett. 2005 Jan;12(1):31-9
pubmed: 15638801
Microbiology (Reading). 2000 Oct;146 ( Pt 10):2665-2670
pubmed: 11021941