Effect of Evening Primrose Vaginal Capsule on Cervix Preparation and Duration of First Stage of Labor in Nulliparous Women Referred to Fatemieh Hospital in Hamadan, Iran: A Single-blind Randomized Controlled Trial.
Cervical ripening
cervical ripening
clinical trial
evening primrose oil
first stage labor
primiparity
Journal
Current drug research reviews
ISSN: 2589-9783
Titre abrégé: Curr Drug Res Rev
Pays: United Arab Emirates
ID NLM: 101735701
Informations de publication
Date de publication:
2022
2022
Historique:
received:
20
10
2021
revised:
28
01
2022
accepted:
22
02
2022
pubmed:
21
4
2022
medline:
27
10
2022
entrez:
20
4
2022
Statut:
ppublish
Résumé
Cervix preparation is one of the main steps in the onset of labor and is very important for success in initiating or inducing labor. The present study aimed at investigating the effect of evening primrose vaginal capsule on the preparation of cervix and the consequences of labor in nulliparous women. This randomized clinical trial study was conducted in 2018 on 100 nulliparous women referred to Fatemieh Hospital in Hamadan. In intervention group (50 people), one evening primrose capsule (500 mg) was used vaginally and then two hours later, another capsule was used, and placebo was used in the control group (50 people). Then, the dilatation, effacement, Bishop scores and duration of the first stage of the labor were compared in two groups after 4 hours. Statistical analysis was performed with SPSS 21. The significance level was considered to be 0.05. There was a statistically significant difference in the mean score and standard deviation of dilatation, effacement of cervix, bi-shop scores and duration of the first stage of labor four hours after the intervention in the intervention and Placebo groups by controlling the effect of potential confounding factors (P <0.001). The results showed that the use of evening primrose vaginal capsules can reduce the length of the first stage of labor, improve Bishop score, and soften and ripen the cervix.
Sections du résumé
BACKGROUND
BACKGROUND
Cervix preparation is one of the main steps in the onset of labor and is very important for success in initiating or inducing labor.
OBJECTIVE
OBJECTIVE
The present study aimed at investigating the effect of evening primrose vaginal capsule on the preparation of cervix and the consequences of labor in nulliparous women.
METHODS
METHODS
This randomized clinical trial study was conducted in 2018 on 100 nulliparous women referred to Fatemieh Hospital in Hamadan. In intervention group (50 people), one evening primrose capsule (500 mg) was used vaginally and then two hours later, another capsule was used, and placebo was used in the control group (50 people). Then, the dilatation, effacement, Bishop scores and duration of the first stage of the labor were compared in two groups after 4 hours. Statistical analysis was performed with SPSS 21. The significance level was considered to be 0.05.
RESULTS
RESULTS
There was a statistically significant difference in the mean score and standard deviation of dilatation, effacement of cervix, bi-shop scores and duration of the first stage of labor four hours after the intervention in the intervention and Placebo groups by controlling the effect of potential confounding factors (P <0.001).
CONCLUSION
CONCLUSIONS
The results showed that the use of evening primrose vaginal capsules can reduce the length of the first stage of labor, improve Bishop score, and soften and ripen the cervix.
Identifiants
pubmed: 35440333
pii: CDRR-EPUB-122637
doi: 10.2174/2589977514666220418091807
doi:
Substances chimiques
Capsules
0
Types de publication
Randomized Controlled Trial
Clinical Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
247-253Subventions
Organisme : Hamadan University of Medical Sciences
ID : 9707174139
Informations de copyright
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