Priorities for cancer research in low- and middle-income countries: a global perspective.


Journal

Nature medicine
ISSN: 1546-170X
Titre abrégé: Nat Med
Pays: United States
ID NLM: 9502015

Informations de publication

Date de publication:
04 2022
Historique:
received: 22 12 2021
accepted: 09 02 2022
entrez: 20 4 2022
pubmed: 21 4 2022
medline: 22 4 2022
Statut: ppublish

Résumé

Cancer research currently is heavily skewed toward high-income countries (HICs), with little research conducted in, and relevant to, the problems of low- and middle-income countries (LMICs). This regional discordance in cancer knowledge generation and application needs to be rebalanced. Several gaps in the research enterprise of LMICs need to be addressed to promote regionally relevant research, and radical rethinking is needed to address the burning issues in cancer care in these regions. We identified five top priorities in cancer research in LMICs based on current and projected needs: reducing the burden of patients with advanced disease; improving access and affordability, and outcomes of cancer treatment; value-based care and health economics; quality improvement and implementation research; and leveraging technology to improve cancer control. LMICs have an excellent opportunity to address important questions in cancer research that could impact cancer control globally. Success will require collaboration and commitment from governments, policy makers, funding agencies, health care organizations and leaders, researchers and the public.

Identifiants

pubmed: 35440716
doi: 10.1038/s41591-022-01738-x
pii: 10.1038/s41591-022-01738-x
pmc: PMC9108683
mid: NIHMS1804393
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

649-657

Subventions

Organisme : World Health Organization
ID : 001
Pays : International
Organisme : Cancer Research UK
ID : 29186
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/W023903/1
Pays : United Kingdom
Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States

Informations de copyright

© 2022. Springer Nature America, Inc.

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Auteurs

C S Pramesh (CS)

Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India. prameshcs@tmc.gov.in.

Rajendra A Badwe (RA)

Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.

Nirmala Bhoo-Pathy (N)

Centre for Epidemiology and Evidence-Based Practice, University of Malaya, Kuala Lumpur, Malaysia.

Christopher M Booth (CM)

Departments of Oncology and Public Health Sciences, Queen's University, Kingston, Ontario, Canada.

Girish Chinnaswamy (G)

Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.

Anna J Dare (AJ)

Department of Surgery, University of Toronto, Toronto, Ontario, Canada.

Victor Piana de Andrade (VP)

A.C. Camargo Cancer Center, São Paulo, Brazil.

David J Hunter (DJ)

Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Satish Gopal (S)

Centre for Global Health, National Cancer Institute, Rockville, MD, USA.

Mary Gospodarowicz (M)

Princess Margaret Cancer Centre and University of Toronto, Toronto, Ontario, Canada.

Sanjeeva Gunasekera (S)

National Cancer Institute Sri Lanka, Colombo, Sri Lanka.

Andre Ilbawi (A)

World Health Organization, Geneva, Switzerland.

Sharon Kapambwe (S)

World Health Organization Africa, Harare, Zimbabwe.

Peter Kingham (P)

Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Tezer Kutluk (T)

Faculty of Medicine and Cancer Institute, Hacettepe University, Ankara, Turkey.

Nirmal Lamichhane (N)

B.P. Koirala Memorial Cancer Hospital, Bharatpur, Nepal.

Miriam Mutebi (M)

Aga Khan University, Nairobi, Kenya.

Jackson Orem (J)

Uganda Cancer Institute, Kampala, Uganda.

Groesbeck Parham (G)

University of North Carolina, Chapel Hill, NC, USA.

Priya Ranganathan (P)

Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.

Manju Sengar (M)

Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.

Richard Sullivan (R)

Institute of Cancer Policy, King's College London, London, UK.

Soumya Swaminathan (S)

World Health Organization, Geneva, Switzerland.

Ian F Tannock (IF)

Princess Margaret Cancer Centre and University of Toronto, Toronto, Ontario, Canada.

Vivek Tomar (V)

Rise To Survive Cancer, New Delhi, India.

Verna Vanderpuye (V)

National Center for Radiotherapy Oncology and Nuclear Medicine and Korle Bu Teaching Hospital, Accra, Ghana.

Cherian Varghese (C)

World Health Organization, Geneva, Switzerland.

Elisabete Weiderpass (E)

International Association for Research on Cancer, Lyon, France.

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