Artificial intelligence supporting cancer patients across Europe-The ASCAPE project.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2022
Historique:
received: 08 02 2022
accepted: 11 02 2022
entrez: 21 4 2022
pubmed: 22 4 2022
medline: 26 4 2022
Statut: epublish

Résumé

Breast and prostate cancer survivors can experience impaired quality of life (QoL) in several QoL domains. The current strategy to support cancer survivors with impaired QoL is suboptimal, leading to unmet patient needs. ASCAPE aims to provide personalized- and artificial intelligence (AI)-based predictions for QoL issues in breast- and prostate cancer patients as well as to suggest potential interventions to their physicians to offer a more modern and holistic approach on cancer rehabilitation. An AI-based platform aiming to predict QoL issues and suggest appropriate interventions to clinicians will be built based on patient data gathered through medical records, questionnaires, apps, and wearables. This platform will be prospectively evaluated through a longitudinal study where breast and prostate cancer survivors from four different study sites across the Europe will be enrolled. The evaluation of the AI-based follow-up strategy through the ASCAPE platform will be based on patients' experience, engagement, and potential improvement in QoL during the study as well as on clinicians' view on how ASCAPE platform impacts their clinical practice and doctor-patient relationship, and their experience in using the platform. ASCAPE is the first research project that will prospectively investigate an AI-based approach for an individualized follow-up strategy for patients with breast- or prostate cancer focusing on patients' QoL issues. ASCAPE represents a paradigm shift both in terms of a more individualized approach for follow-up based on QoL issues, which is an unmet need for cancer survivors, and in terms of how to use Big Data in cancer care through democratizing the knowledge and the access to AI and Big Data related innovations. Trial Registration on clinicaltrials.gov: NCT04879563.

Identifiants

pubmed: 35446854
doi: 10.1371/journal.pone.0265127
pii: PONE-D-22-02528
pmc: PMC9022843
doi:

Banques de données

ClinicalTrials.gov
['NCT04879563']

Types de publication

Clinical Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0265127

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Lazaros Tzelves (L)

National and Kapodistrian University of Athens Faculty of Medicine Marousi, 2nd Department of Urology, Athens, Greece.

Ioannis Manolitsis (I)

National and Kapodistrian University of Athens Faculty of Medicine Marousi, 2nd Department of Urology, Athens, Greece.

Ioannis Varkarakis (I)

National and Kapodistrian University of Athens Faculty of Medicine Marousi, 2nd Department of Urology, Athens, Greece.

Mirjana Ivanovic (M)

Faculty of Sciences, University of Novi Sad, Novi Sad, Serbia.

Miltiadis Kokkonidis (M)

Intrasoft International Ltd., Luxembourg, Luxembourg.

Cristina Sabater Useros (CS)

ATOS SE, Madrid, Spain.

Thanos Kosmidis (T)

CareAcross Ltd, London, United Kingdom.

Montserrat Muñoz (M)

Department of Medical Oncology, Hospital Clinic of Barcelona, Barcelona, Spain.

Imma Grau (I)

Department of Medical Oncology, Hospital Clinic of Barcelona, Barcelona, Spain.

Manos Athanatos (M)

Foundation for Research and Technology-Hellas (FORTH), Heraklion, Crete, Greece.

Anamaria Vizitiu (A)

Siemens SRL, Bucuresti, Romania.

Konstantinos Lampropoulos (K)

Department of Electrical and Computer Engineering, University of Patras, Patras, Greece.

Tzortzia Koutsouri (T)

Sphynx Technology Solutions AG, Zug, Switzerland.

Dimitra Stefanatou (D)

Arthur's Legal, Amsterdam, The Netherlands.

Konstantinos Perrakis (K)

UBITECH Research Department, UBITECH Ltd., Athens, Greece.

Christina Stratigaki (C)

UBITECH Research Department, UBITECH Ltd., Athens, Greece.

Serge Autexier (S)

German Research Center for Artificial Intelligence (DFKI), Bremen, Germany.

Paris Kosmidis (P)

CareAcross Ltd, London, United Kingdom.
Second Medical Oncology Department, Hygeia Hospital, Athens, Greece.

Antonis Valachis (A)

Department of Oncology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

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Classifications MeSH