Treatment of Permethrin Toxicosis in Cats by Intravenous Lipid Emulsion.
antidote
feline
lipid resuscitation
pyrethroids
soybean oil
Journal
Toxics
ISSN: 2305-6304
Titre abrégé: Toxics
Pays: Switzerland
ID NLM: 101639637
Informations de publication
Date de publication:
30 Mar 2022
30 Mar 2022
Historique:
received:
16
03
2022
revised:
28
03
2022
accepted:
29
03
2022
entrez:
21
4
2022
pubmed:
22
4
2022
medline:
22
4
2022
Statut:
epublish
Résumé
In this study, the clinical response to treatment with intravenous lipid emulsion (ILE) for nine cats intoxicated with permethrin has been described. The enrolled cats showed acute onset of seizures, tremors and hypersalivation that were partially controlled with the administration of benzodiazepines and intravenous fluid therapy. Due to worsening clinical signs, intravenous lipid emulsion (intralipid 20%; 1.5 mL/kg in bolus, followed by 15 mL/kg for 1 h in infusion) was administered. After ILE treatment, all cats recovered rapidly and were discharged within 24-54 h. Intravenous lipid emulsion appears to be a relatively safe and inexpensive alternative, with a short hospitalization time. Intravenous lipid emulsion could be an interesting therapeutic option in emergency and critical care protocols for permethrin toxicosis.
Sections du résumé
BACKGROUND
BACKGROUND
In this study, the clinical response to treatment with intravenous lipid emulsion (ILE) for nine cats intoxicated with permethrin has been described.
METHODS
METHODS
The enrolled cats showed acute onset of seizures, tremors and hypersalivation that were partially controlled with the administration of benzodiazepines and intravenous fluid therapy. Due to worsening clinical signs, intravenous lipid emulsion (intralipid 20%; 1.5 mL/kg in bolus, followed by 15 mL/kg for 1 h in infusion) was administered.
RESULTS
RESULTS
After ILE treatment, all cats recovered rapidly and were discharged within 24-54 h. Intravenous lipid emulsion appears to be a relatively safe and inexpensive alternative, with a short hospitalization time.
CONCLUSIONS
CONCLUSIONS
Intravenous lipid emulsion could be an interesting therapeutic option in emergency and critical care protocols for permethrin toxicosis.
Identifiants
pubmed: 35448426
pii: toxics10040165
doi: 10.3390/toxics10040165
pmc: PMC9029646
pii:
doi:
Types de publication
Case Reports
Langues
eng
Références
Vet Med (Auckl). 2017 Oct 30;8:77-85
pubmed: 30050859
J Feline Med Surg. 2010 Feb;12(2):61-71
pubmed: 19897392
Open Vet J. 2015;5(2):113-21
pubmed: 26623376
Reg Anesth Pain Med. 2018 Feb;43(2):138-149
pubmed: 29356774
J Am Vet Med Assoc. 1998 Sep 15;213(6):800-1
pubmed: 9743715
Vet Rec. 2012 Apr 21;170(16):415
pubmed: 22271801
Can Vet J. 2014 Jan;55(1):1253-4
pubmed: 24381347
Reg Anesth Pain Med. 2010 Mar-Apr;35(2):140-4
pubmed: 20301820
J Vet Emerg Crit Care (San Antonio). 2015 Sep-Oct;25(5):597-605
pubmed: 26088727
Anesthesiology. 2006 Jul;105(1):217-8
pubmed: 16810015
Vet Rec. 2000 Nov 25;147(22):639
pubmed: 11128081
J Vet Emerg Crit Care (San Antonio). 2013 Jul-Aug;23(4):436-41
pubmed: 23855545