Protein Kinase A Regulates Autophagy-Associated Proteins Impacting Growth and Virulence of

Aspergillus aspergillosis autophagy cell wall filamentous fungi nutrient sensing pathogenesis phosphorylation protein kinase A proteomics

Journal

Journal of fungi (Basel, Switzerland)
ISSN: 2309-608X
Titre abrégé: J Fungi (Basel)
Pays: Switzerland
ID NLM: 101671827

Informations de publication

Date de publication:
30 Mar 2022
Historique:
received: 28 02 2022
revised: 14 03 2022
accepted: 28 03 2022
entrez: 21 4 2022
pubmed: 22 4 2022
medline: 22 4 2022
Statut: epublish

Résumé

Cellular recycling via autophagy-associated proteins is a key catabolic pathway critical to invasive fungal pathogen growth and virulence in the nutrient-limited host environment. Protein kinase A (PKA) is vital for the growth and virulence of numerous fungal pathogens. However, the underlying basis for its regulation of pathogenesis remains poorly understood in any species. Our

Identifiants

pubmed: 35448585
pii: jof8040354
doi: 10.3390/jof8040354
pmc: PMC9029100
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : NIAID NIH HHS
ID : R21 AI132911
Pays : United States
Organisme : National Institute of Allergy and Infectious Diseases
ID : 5R21AI132911-02

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Auteurs

E Keats Shwab (EK)

Department of Pediatrics, Division of Pediatric Infectious Diseases, Duke University Medical Center, Durham, NC 27710, USA.

Praveen R Juvvadi (PR)

Department of Pediatrics, Division of Pediatric Infectious Diseases, Duke University Medical Center, Durham, NC 27710, USA.

Shareef K Shaheen (SK)

Department of Pediatrics, Division of Pediatric Infectious Diseases, Duke University Medical Center, Durham, NC 27710, USA.

John Allen (J)

Department of Pediatrics, Division of Pediatric Infectious Diseases, Duke University Medical Center, Durham, NC 27710, USA.

Greg Waitt (G)

Duke Proteomics Core Facility, Institute for Genome Sciences and Policy, Duke University, Durham, NC 27701, USA.

Erik J Soderblom (EJ)

Duke Proteomics Core Facility, Institute for Genome Sciences and Policy, Duke University, Durham, NC 27701, USA.

Yohannes G Asfaw (YG)

Department of Laboratory Animal Resources, Duke University Medical Center, Durham, NC 27710, USA.

M Arthur Moseley (MA)

Duke Proteomics Core Facility, Institute for Genome Sciences and Policy, Duke University, Durham, NC 27701, USA.

William J Steinbach (WJ)

Department of Pediatrics, Division of Pediatric Infectious Diseases, Duke University Medical Center, Durham, NC 27710, USA.
Department of Molecular Genetics & Microbiology, Duke University Medical Center, Durham, NC 27710, USA.

Classifications MeSH