Diagnostic Performance of Preoperative Choline-PET/CT in Patients Undergoing Salvage Lymph Node Dissection for Recurrent Prostate Cancer: A Multicenter Experience.
positron emission tomography computed tomography
predictive value of tests
prostatic neoplasms
salvage therapy
sensitivity and specificity
Journal
Tomography (Ann Arbor, Mich.)
ISSN: 2379-139X
Titre abrégé: Tomography
Pays: Switzerland
ID NLM: 101671170
Informations de publication
Date de publication:
11 04 2022
11 04 2022
Historique:
received:
25
02
2022
revised:
31
03
2022
accepted:
07
04
2022
entrez:
21
4
2022
pubmed:
22
4
2022
medline:
26
4
2022
Statut:
epublish
Résumé
We aimed to retrospectively analyze consecutive prostate cancer patients diagnosed with biochemical or clinical recurrence after local treatment with curative intent, with no evidence of distant metastases, who underwent positron emission tomography/computed tomography (PET/CT) with choline followed by salvage lymph node dissection (SLND) in three academic centers between 2013 and 2020. A total of 27 men were included in the analyses. Sensitivity, specificity, positive and negative predictive values, and accuracy of choline-PET/CT in predicting pathology-proven lymph node involvement were 75%, 43%, 79%, 38% and 67% on per-patient and 70%, 86%, 80%, 78%, and 79% on per-site analyses, respectively, with the differences in specificity and NPV between per-patient and per-site analyses being statistically significant (
Identifiants
pubmed: 35448723
pii: tomography8020089
doi: 10.3390/tomography8020089
pmc: PMC9031841
doi:
Substances chimiques
Choline
N91BDP6H0X
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
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