Cost and public reimbursement of cancer medicines in the UK and the Republic of Ireland.
Cancer drugs
Oncology
Pharmacoeconomics
Journal
Irish journal of medical science
ISSN: 1863-4362
Titre abrégé: Ir J Med Sci
Pays: Ireland
ID NLM: 7806864
Informations de publication
Date de publication:
Apr 2023
Apr 2023
Historique:
received:
26
10
2021
accepted:
28
03
2022
medline:
4
4
2023
pubmed:
23
4
2022
entrez:
22
4
2022
Statut:
ppublish
Résumé
There are disparities in the availability of systemic anticancer therapies (SACTs) globally. We set out to investigate the cost and reimbursement of SACTs in the United Kingdom (UK) and the Republic of Ireland (ROI) in conjunction with efficacy and licensing authority decisions in the United States (US) and the European Union (EU). We sought data pertaining to licensing in the EU, reimbursement in ROI/UK and cost/efficacy of SACTs licensed by the Food and Drug Administration (FDA) between January 2015 and May 2021. Independent samples t tests, chi-square test and Pearson's correlation were used for statistical analysis. We identified that the majority of FDA-approved regimens are licensed by the European Medicines Agency (EMA) (n = 91, 67.9%). However, only a minority of these are currently reimbursed in the UK (n = 60, 45%) or the ROI (n = 28, 21%) as of the 1 Our study highlights that many licensed systemic anticancer treatments are not currently reimbursed in ROI/UK. The high cost of these medicines is independent of the presence of an OS benefit. Collaboration between regulatory agencies, governments and industry partners is needed to ensure health expenditure is directed towards the most effective treatments.
Identifiants
pubmed: 35449390
doi: 10.1007/s11845-022-02990-3
pii: 10.1007/s11845-022-02990-3
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
541-548Informations de copyright
© 2022. The Author(s), under exclusive licence to Royal Academy of Medicine in Ireland.
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