The Impact of Curcumin on the Inflammatory Profile of SW982 Cells in a Rheumatoid Arthritis Model.


Journal

Journal of immunology research
ISSN: 2314-7156
Titre abrégé: J Immunol Res
Pays: Egypt
ID NLM: 101627166

Informations de publication

Date de publication:
2022
Historique:
received: 04 01 2022
revised: 06 03 2022
accepted: 15 03 2022
entrez: 22 4 2022
pubmed: 23 4 2022
medline: 26 4 2022
Statut: epublish

Résumé

Rheumatoid arthritis (RA) is one of the most prevalent autoimmune diseases, affecting approximately 1% of the total global population. Curcumin, a natural polyphenol is a substance that could potentially mitigate the course of this disease. To evaluate curcumin's anti-inflammatory impact on synoviocytes in the RA model, a set of experiments was conducted on SW982 cells, stimulated by IL-1

Identifiants

pubmed: 35450396
doi: 10.1155/2022/1208970
pmc: PMC9018200
doi:

Substances chimiques

Interleukin-6 0
Tumor Necrosis Factor-alpha 0
Matrix Metalloproteinase 1 EC 3.4.24.7
Curcumin IT942ZTH98

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1208970

Informations de copyright

Copyright © 2022 Kamil Więcek et al.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Kamil Więcek (K)

Department of Clinical and Experimental Pathology, Wroclaw Medical University, Marcinkowskiego 1, 50-368 Wroclaw, Poland.

Piotr Kupczyk (P)

Department of Clinical and Experimental Pathology, Wroclaw Medical University, Marcinkowskiego 1, 50-368 Wroclaw, Poland.

Grzegorz Chodaczek (G)

Bioimaging Laboratory, Łukasiewicz Research Network-PORT Polish Center for Technology Development, Stablowicka 147, 54-066 Wroclaw, Poland.

Marta Woźniak (M)

Department of Clinical and Experimental Pathology, Wroclaw Medical University, Marcinkowskiego 1, 50-368 Wroclaw, Poland.

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Classifications MeSH