Extracorporeal membrane oxygenation during the first three waves of the coronavirus disease 2019 pandemic: A retrospective single-center registry study.


Journal

Artificial organs
ISSN: 1525-1594
Titre abrégé: Artif Organs
Pays: United States
ID NLM: 7802778

Informations de publication

Date de publication:
Sep 2022
Historique:
revised: 13 03 2022
received: 23 12 2021
accepted: 11 04 2022
pubmed: 23 4 2022
medline: 25 8 2022
entrez: 22 4 2022
Statut: ppublish

Résumé

Despite increasing knowledge about the optimal treatment for patients with severe COVID-19, data from different cohorts suggested that survival of patients treated with ECMO seemed to decline over the course of the pandemic. In this non-interventional retrospective single-center registry study we analyzed all consecutive patients tested positive for SARS-CoV-2 infection and supported with VV ECMO in our center during the first three waves of the pandemic. From March 2020 through June 2021, 59 patients have been included. Overall 90-day survival was 32%. Besides changes in drug treatment for COVID-19 and a lower PaO VV ECMO has shown to be a feasible and safe support option for patients with severe respiratory failure due to COVID-19. The results from this single-center study confirm findings from other cohorts showing declining survival rates of patients treated with VV ECMO during the COVID-19 pandemic, however, the specific reasons for this finding remain unclear.

Sections du résumé

BACKGROUND BACKGROUND
Despite increasing knowledge about the optimal treatment for patients with severe COVID-19, data from different cohorts suggested that survival of patients treated with ECMO seemed to decline over the course of the pandemic.
METHODS METHODS
In this non-interventional retrospective single-center registry study we analyzed all consecutive patients tested positive for SARS-CoV-2 infection and supported with VV ECMO in our center during the first three waves of the pandemic. From March 2020 through June 2021, 59 patients have been included.
RESULTS RESULTS
Overall 90-day survival was 32%. Besides changes in drug treatment for COVID-19 and a lower PaO
CONCLUSIONS CONCLUSIONS
VV ECMO has shown to be a feasible and safe support option for patients with severe respiratory failure due to COVID-19. The results from this single-center study confirm findings from other cohorts showing declining survival rates of patients treated with VV ECMO during the COVID-19 pandemic, however, the specific reasons for this finding remain unclear.

Identifiants

pubmed: 35451145
doi: 10.1111/aor.14270
pmc: PMC9111358
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1876-1885

Informations de copyright

© 2022 The Authors. Artificial Organs published by International Center for Artificial Organ and Transplantation (ICAOT) and Wiley Periodicals LLC.

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Auteurs

Eugen Widmeier (E)

Interdisciplinary Medical Intensive Care, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Tobias Wengenmayer (T)

Interdisciplinary Medical Intensive Care, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Freiburg, Germany.

Sven Maier (S)

Department of Cardiovascular Surgery, Heart Center, University of Freiburg, Freiburg, Germany.

Christoph Benk (C)

Department of Cardiovascular Surgery, Heart Center, University of Freiburg, Freiburg, Germany.

Viviane Zotzmann (V)

Interdisciplinary Medical Intensive Care, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Freiburg, Germany.

Dawid L Staudacher (DL)

Interdisciplinary Medical Intensive Care, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Freiburg, Germany.

Alexander Supady (A)

Interdisciplinary Medical Intensive Care, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Freiburg, Germany.
Heidelberg Institute of Global Health, University of Heidelberg, Freiburg, Germany.

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