Core-Sheath-Like Poly(Ethylene Oxide)/Beeswax Composite Fibers Prepared by Single-Spinneret Electrospinning. Antibacterial, Antifungal, and Antitumor Activities.
anticancer
antimicrobial
beeswax
core-sheath
electrospinning
Journal
Macromolecular bioscience
ISSN: 1616-5195
Titre abrégé: Macromol Biosci
Pays: Germany
ID NLM: 101135941
Informations de publication
Date de publication:
06 2022
06 2022
Historique:
revised:
24
03
2022
received:
13
01
2022
pubmed:
23
4
2022
medline:
15
6
2022
entrez:
22
4
2022
Statut:
ppublish
Résumé
Composite fibrous materials are prepared from poly(ethylene oxide) (PEO) and beeswax (BW) by single-spinneret electrospinning using chloroform as a common solvent. The obtained fibers have core-sheath-like structure, as evidenced by the water contact angle values and corroborated by the results on the elemental composition of the fiber's surface determined by X-ray photoelectron spectroscopy (XPS) and by analyses with scanning electron microscopy of fibers before and after selective extraction of PEO or BW. Furthermore, the core-sheath-like structure is proven by transmission electron microscopy. This is attributed to self-assembly of BW molecules on the surface of the formed fibers driven by the incompatibility between PEO and BW. 5-Nitro-8-hydroxyquinoline (NQ) is embedded as a model drug with antibacterial, antifungal, and anticancer properties in the PEO/BW fibrous materials. XPS analyses reveal that NQ is present on the surface of the PEO/BW/NQ materials. Using a purposely designed cell for fixation of the fibrous materials the NQ release in phosphate buffer solution with рН 7.4 is followed. The new PEO/BW/NQ fibrous materials exhibit antibacterial activity against S. aureus and E. coli, antifungal effect against C. albicans, and selective anticancer activity against HeLa (human cervical adenocarcinoma cells) and SH-4 (human melanoma cells) cell lines.
Identifiants
pubmed: 35451564
doi: 10.1002/mabi.202200015
doi:
Substances chimiques
Anti-Bacterial Agents
0
Antifungal Agents
0
Waxes
0
beeswax
2ZA36H0S2V
Polyethylene Glycols
3WJQ0SDW1A
Ethylene Oxide
JJH7GNN18P
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2200015Informations de copyright
© 2022 Wiley-VCH GmbH.
Références
D. T. Yazıcı, A. Yener, J. Polym. Eng. 2019, 39, 178.
S. Bogdanov, Bee World 2004, 85, 46.
F. Fratini, G. Cilia, B. Turchi, A. Felicioli, Asian Pac. J. Trop. Med. 2016, 9, 839.
D. Paneva, М. Ignatova, N. Manolova, I. Rashkov, Nanofibers: Fabrication, Performance, and Applications (Ed: W. N. Chang), Nova Science Publishers, Inc., New York 2009.
M. Ignatova, N. Manolova, I. Rashkov, Macromol. Biosci. 2013, 13, 860.
M. Abrigo, S. L. Mcarthur, P. Kingshott, Macromol. Biosci. 2014, 14, 772.
A. Haider, S. Haider, I. -. K. Kang, Arabian J. Chem. 2018, 11, 1165.
A. Luraghi, F. Peri, L. Moroni, J. Controlled Release 2021, 334, 463.
C. R. Reshmi, S. P. Sundaran, A. Juraij, S. Athiyanathil, RSC Adv. 2017, 7, 2092.
J. Zou, M. Lu, S. Chen, C. Cai, Z. Yao, W. Cui, C. Fan, S. Liu, Mater. Sci. Eng., Proc. Conf. 2020, 116, 111166.
L. Ma, L.i Deng, J. Chen, Drug Dev. Ind. Pharm. 2014, 40, 845.
J. Deitzel, Polymer 2001, 42, 8163.
M. Spasova, N. Manolova, D. Paneva, I. Rashkov, e-Polymers 2004, 056, 1.
P. Filip, P. Peer, Processes 2019, 7, 1.
W. K. Son, J. I. H. O. Youk, T. S. Lee, W. H. O. Park, Polymer 2004, 45, 2959.
J. -. W. Lu, Y. -. L. Zhu, Z. -. X. Guo, P. Hu, J. Yu, Polymer 2006, 47, 8026.
H. -. J. Jin, S. V. Fridrikh, G. C. Rutledge, D. L. Kaplan, Biomacromolecules 2002, 3, 1233.
R. Serôdio, S. L. Schickert, A. R. Costa-Pinto, J. R. Dias, P. L. Granja, F. Yang, A. L. Oliveira, Mater. Sci. Eng., Proc. Conf. 2019, 98, 969.
Z. Ruguo, Z. Hua, Z. Hong, F. Ying, L.i Kun, Z. Wenwen, Procedia Eng. 2011, 18, 101.
J. Janesch, B. Arminger, W. Gindl-Altmutter, C. Hansmann, Prog. Org. Coat. 2020, 148, 105891.
X. Xu, L. Jiang, Z. Zhou, X. Wu, Y. Wang, ACS Appl. Mater. Interfaces 2012, 4, 4331.
N. Rosita, D. Setyawan, W. Soeratri, S. Mrtodihardjo, Int. J. Pharm. Pharm. Sci. 2014, 6, 939.
A. Dinker, M. Agarwal, G. D. Agarwal, Mater. Today: Proc. 2017, 4, 10529.
Y. Abouelhassan, Q. Yang, H. Yousaf, M. T. Nguyen, M. Rolfe, G. S. Schultz, R. W. Huigens, III, Int. J. Antimicrob. Agents 2017, 49, 247.
H. Jiang, J. E. Taggart, X. Zhang, D. M. Benbrook, S. E. Lind, W. -. Q. Ding, Cancer Lett. 2011, 312, 11.
N. A. M. Barakat, M. A. Kanjwal, F. A. Sheikh, H. Y. Kim, Polymer 2009, 50, 4389.
H. Penchev, D. Paneva, N. Manolova, I. Rashkov, Carbohydr. Res. 2010, 345, 2374.
M. F. Abdullah, T. Nuge, A. Andriyana, B. C. Ang, F. Muhamad, Polymers 2019, 11, 2008.
E. Korina, O. Stoilova, N. Manolova, I. Rashkov, J. Environ. Chem. Eng. 2018, 6, 2075.
J. -. F. Zhang, D. -. Z. Yang, F. Xu, Z.i-P. Zhang, R. -. X. Yin, J. Nie, Macromolecules 2009, 42, 5278.
T. Xu, H. Yang, D. Yang, Z. -. Z. Yu, ACS Appl. Mater. Interfaces 2017, 9, 21094.
R. Cherdtrakulkiat, S. Boonpangrak, N. Sinthupoom, S. Prachayasittikul, S. Ruchirawat, V. Prachayasittikul, Biochem. Biophys. Rep. 2016, 6, 135.
S. Syarifah, M. Y. Nurhanan, J. M. Haffiz, A. M. Ilham, K. Getha, O. Asiah, I. Norhayati, H. L. Sahira, S. A. Suryani, J. Trop. For. Sci. 2011, 23, 89.
M. Kurata, Y. Tsunashima, Polymer Handbook, Vol. 2, 4th Edition (Eds: J. Brandrup, E.H. Immergut, E.A. Grulke), John Wiley & Sons, Inc., Hoboken, New Jersey 1999.
M. Spasova, R. Mincheva, D. Paneva, N. Manolova, I. Rashkov, J. Bioact. Compat. Polym. 2006, 21, 465.
T. Mosmann, J. Immunol. Methods 1983, 65, 55.
S. I. A. Wahab, A. B. Abdul, A. S. Alzubairi, M. M. Elhassan, S. Mohan, J. Biomed. Biotechnol. 2009, 2009, 769568.
S. -. C. Tsai, C. -. C. Lu, C. -. Y. Lee, Y. -. C. Lin, J. -. G. Chung, S. -. C. Kuo, S. Amagaya, F.-N.a Chen, M. Y. Chen, S. -. F. Chan, J. -. S. Yang, Int. J. Oncol. 2012, 41, 1683.