Autoimmune Encephalitis in COVID-19 Infection: Our Experience and Systematic Review of the Literature.
COVID-19 infection
autoimmune encephalitis
voltage-gated potassium channels antibody
Journal
Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304
Informations de publication
Date de publication:
25 Mar 2022
25 Mar 2022
Historique:
received:
05
02
2022
revised:
02
03
2022
accepted:
21
03
2022
entrez:
23
4
2022
pubmed:
24
4
2022
medline:
24
4
2022
Statut:
epublish
Résumé
The neurologic complications of COVID-19 infection are frequent in hospitalized patients; a high percentage of them present neurologic manifestations at some point during the course of their disease. Headache, muscle pain, encephalopathy and dizziness are among the most common complications. Encephalitis is an inflammatory condition with many etiologies. There are several forms of encephalitis associated with antibodies against intracellular neuronal proteins, cell surfaces or synaptic proteins, referred to as autoimmune encephalitis. Several case reports published in the literature document autoimmune encephalitis cases triggered by COVID-19 infection. Our paper first presents our experience in this issue and then systematically reviews the literature on autoimmune encephalitis that developed in the background of SARS-CoV-2 infections and also discusses the possible pathophysiological mechanisms of auto-immune-mediated damage to the nervous system. This review contributes to improve the management and prognosis of COVID-19-related autoimmune encephalitis.
Identifiants
pubmed: 35453524
pii: biomedicines10040774
doi: 10.3390/biomedicines10040774
pmc: PMC9024859
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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