COVID-19 Infection Induce miR-371a-3p Upregulation Resulting in Influence on Male Fertility.
COVID-19
SARS-CoV-2
androgen receptor
male infertility
miR-371a-3p
Journal
Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304
Informations de publication
Date de publication:
06 Apr 2022
06 Apr 2022
Historique:
received:
28
01
2022
revised:
19
03
2022
accepted:
23
03
2022
entrez:
23
4
2022
pubmed:
24
4
2022
medline:
24
4
2022
Statut:
epublish
Résumé
In December 2019, the first case of COVID-19 was reported and since then several groups have already published that the virus can be present in the testis. To study the influence of SARS-CoV-2 which cause a dysregulation of the androgen receptor (AR) level, thereby leading to fertility problems and inducing germ cell testicular changes in patients after the infection. Formalin-Fixed-Paraffin-Embedded (FFPE) testicular samples from patients who died with or as a result of COVID-19 (
Identifiants
pubmed: 35453608
pii: biomedicines10040858
doi: 10.3390/biomedicines10040858
pmc: PMC9033010
pii:
doi:
Types de publication
Journal Article
Langues
eng
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