Single-Cell Sequencing: Ariadne's Thread in the Maze of Acute Myeloid Leukemia.
acute myeloid leukemia
clonal evolution
clonal heterogeneity
single-cell DNA sequencing
single-cell RNA sequencing
Journal
Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402
Informations de publication
Date de publication:
15 Apr 2022
15 Apr 2022
Historique:
received:
07
03
2022
revised:
12
04
2022
accepted:
14
04
2022
entrez:
23
4
2022
pubmed:
24
4
2022
medline:
24
4
2022
Statut:
epublish
Résumé
Acute myeloid leukemia (AML) is a haematological neoplasm resulting from the accumulation of genetic and epigenetic alterations. Patients' prognoses vary with AML genetic heterogeneity, which hampers successful treatments. Single-cell approaches have provided new insights of the clonal architecture of AML, revealing the mutational history from diagnosis, during treatment and to relapse. In this review, we imagine single-cell technologies as the Ariadne's thread that will guide us out of the AML maze, provide a precise identikit of the leukemic cell at single-cell resolution and explore genomic, transcriptomic, epigenetic and proteomic levels.
Identifiants
pubmed: 35454044
pii: diagnostics12040996
doi: 10.3390/diagnostics12040996
pmc: PMC9024495
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Pediatr Blood Cancer. 2018 Feb;65(2):
pubmed: 29090521
Clin Epigenetics. 2017 Feb 10;9:17
pubmed: 28203307
Nat Protoc. 2017 Jan;12(1):44-73
pubmed: 27929523
Nat Commun. 2019 Aug 14;10(1):3660
pubmed: 31413257
N Engl J Med. 2016 Jun 9;374(23):2209-2221
pubmed: 27276561
Science. 2014 Feb 14;343(6172):776-9
pubmed: 24531970
Nat Biotechnol. 2020 Jun;38(6):708-714
pubmed: 32518404
Blood Adv. 2020 Mar 10;4(5):943-952
pubmed: 32150611
Genome Res. 2001 Jun;11(6):1095-9
pubmed: 11381035
Blood Adv. 2019 Nov 12;3(21):3322-3332
pubmed: 31698462
Cancer Discov. 2019 Aug;9(8):1050-1063
pubmed: 31088841
Methods Mol Biol. 2018;1783:193-207
pubmed: 29767364
Nat Commun. 2020 Oct 21;11(1):5327
pubmed: 33087716
Science. 2012 Dec 21;338(6114):1622-6
pubmed: 23258894
Nat Commun. 2021 Mar 11;12(1):1583
pubmed: 33707421
Mol Diagn. 2001 Jun;6(2):141-50
pubmed: 11468700
Carcinogenesis. 2018 Jan 12;39(1):2-10
pubmed: 28968750
Cancer Metastasis Rev. 2014 Mar;33(1):115-41
pubmed: 24375388
Br J Haematol. 2016 Feb;172(3):371-383
pubmed: 26597680
Nucleic Acids Res. 2011 Mar;39(4):e19
pubmed: 21071419
J Hematol Oncol. 2012 Jun 18;5:32
pubmed: 22709827
Nat Rev Genet. 2016 Mar;17(3):175-88
pubmed: 26806412
PLoS Genet. 2014 Jul 10;10(7):e1004462
pubmed: 25010716
Genome Biol. 2014 Aug 30;15(8):452
pubmed: 25222669
Am J Hematol. 2019 Aug;94(8):913-920
pubmed: 31145495
Proteomics. 2020 Jul;20(13):e1900228
pubmed: 32181578
Transl Res. 2017 Nov;189:123-135
pubmed: 28802867
J Hematol Oncol. 2020 Sep 25;13(1):128
pubmed: 32977829
Blood. 2017 Jul 6;130(1):48-58
pubmed: 28490572
Leukemia. 2019 May;33(5):1113-1123
pubmed: 30568172
Sci Transl Med. 2012 Aug 29;4(149):149ra118
pubmed: 22932223
N Engl J Med. 2016 Sep 1;375(9):900
pubmed: 27579652
Nat Methods. 2013 Nov;10(11):1096-8
pubmed: 24056875
Blood. 2019 Nov 28;134(22):1891-1901
pubmed: 31697822
Curr Opin Hematol. 2021 Jan;28(1):64-70
pubmed: 33186150
Leuk Res. 2016 Aug;47:41-6
pubmed: 27244256
Methods Mol Biol. 2019;1979:111-132
pubmed: 31028635
Biomark Res. 2021 Jun 27;9(1):50
pubmed: 34176517
Genome Res. 2018 Sep;28(9):1345-1352
pubmed: 30087104
J Genet Genomics. 2014 Oct 20;41(10):513-28
pubmed: 25438696
Pharmacogenomics. 2002 Jul;3(4):557-60
pubmed: 12164778
Cancer Discov. 2019 Aug;9(8):1080-1101
pubmed: 31085557
Cell. 2019 Mar 7;176(6):1265-1281.e24
pubmed: 30827681
Genome Biol. 2017 May 8;18(1):84
pubmed: 28482897
Methods Mol Biol. 2019;1979:73-85
pubmed: 31028633
Nature. 2020 Nov;587(7834):477-482
pubmed: 33116311
Nat Commun. 2019 Jun 20;10(1):2723
pubmed: 31222014
Proc Natl Acad Sci U S A. 1992 Jul 1;89(13):5847-51
pubmed: 1631067
Proc Natl Acad Sci U S A. 2017 May 16;114(20):5237-5242
pubmed: 28461508
Cell. 2019 Jun 13;177(7):1915-1932.e16
pubmed: 31130381
Nature. 2014 Feb 20;506(7488):328-33
pubmed: 24522528
Cancer Res. 2020 Feb 1;80(3):458-470
pubmed: 31784425
Blood. 2019 Jan 3;133(1):7-17
pubmed: 30361262
Nat Rev Genet. 2013 Sep;14(9):618-30
pubmed: 23897237
Crit Rev Oncol Hematol. 2016 Jul;103:62-77
pubmed: 27247119
Sci Rep. 2019 Jul 31;9(1):11119
pubmed: 31366893
J Hematol Oncol. 2021 Jun 9;14(1):91
pubmed: 34108022
Nat Biotechnol. 2018 Jan 10;36(1):46-60
pubmed: 29319699
Sci Transl Med. 2015 Apr 1;7(281):281re2
pubmed: 25834112
Cell. 2014 Mar 27;157(1):41-50
pubmed: 24679525
Genomics. 1992 Jul;13(3):718-25
pubmed: 1639399
Cell Biol Toxicol. 2017 Apr;33(2):83-97
pubmed: 27761761
Genome Biol. 2016 Nov 24;17(1):236
pubmed: 27884178
RNA Biol. 2019 Jun;16(6):785-797
pubmed: 30810468
Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20117-20126
pubmed: 32747558
Nat Methods. 2009 May;6(5):377-82
pubmed: 19349980
Nat Med. 2019 Jan;25(1):103-110
pubmed: 30510255
Oncogenesis. 2018 Apr 20;7(4):34
pubmed: 29674660
Nature. 2012 Jan 11;481(7382):506-10
pubmed: 22237025