Muscle Damage in Dystrophic mdx Mice Is Influenced by the Activity of Ca

Duchenne muscular dystrophy KCa3.1 Kcnn4 fiber size fibroblasts fibrosis grip strength hanging time macrophages neuromuscular junction

Journal

Life (Basel, Switzerland)
ISSN: 2075-1729
Titre abrégé: Life (Basel)
Pays: Switzerland
ID NLM: 101580444

Informations de publication

Date de publication:
05 Apr 2022
Historique:
received: 28 02 2022
revised: 30 03 2022
accepted: 31 03 2022
entrez: 23 4 2022
pubmed: 24 4 2022
medline: 24 4 2022
Statut: epublish

Résumé

Duchenne muscular dystrophy (DMD) is an X-linked disease, caused by a mutant dystrophin gene, leading to muscle membrane instability, followed by muscle inflammation, infiltration of pro-inflammatory macrophages and fibrosis. The calcium-activated potassium channel type 3.1 (K

Identifiants

pubmed: 35455028
pii: life12040538
doi: 10.3390/life12040538
pmc: PMC9025295
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Sapienza University of Rome
ID : RP1201727EA43399
Organisme : Ministry of Education, Universities and Research
ID : PRIN20178L7WRS
Organisme : Ministry of Education, Universities and Research
ID : PRIN2020Z73J5A
Organisme : Italian Association for Cancer Research
ID : IG-23010
Organisme : Duchenne Parent Project Netherlands
ID : small grant proposal ref. 19.006

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Auteurs

Marta Morotti (M)

Department of Physiology and Pharmacology, Sapienza University of Rome, 00185 Rome, Italy.

Stefano Garofalo (S)

Department of Physiology and Pharmacology, Sapienza University of Rome, 00185 Rome, Italy.

Germana Cocozza (G)

Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Neuromed, 86077 Pozzilli, Italy.

Fabrizio Antonangeli (F)

Institute of Molecular Biology and Pathology-National Research Council (CNR), Department of Molecular Medicine, Sapienza University of Rome, 00185 Rome, Italy.

Valeria Bianconi (V)

Institute of Molecular Biology and Pathology-National Research Council (CNR), Department of Biology and Biotechnology, Sapienza University of Rome, 00185 Rome, Italy.

Chiara Mozzetta (C)

Institute of Molecular Biology and Pathology-National Research Council (CNR), Department of Biology and Biotechnology, Sapienza University of Rome, 00185 Rome, Italy.

Maria Egle De Stefano (ME)

Department of Biology and Biotechnology, Sapienza University of Rome, 00185 Rome, Italy.

Riccardo Capitani (R)

Department of Physiology and Pharmacology, Sapienza University of Rome, 00185 Rome, Italy.

Heike Wulff (H)

Department of Pharmacology, University of California, Davis, CA 95616, USA.

Cristina Limatola (C)

Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Neuromed, 86077 Pozzilli, Italy.
Laboratory Affiliated to Istituto Pasteur Italia, Department of Physiology and Pharmacology, Sapienza University of Rome, 00185 Rome, Italy.

Myriam Catalano (M)

Department of Physiology and Pharmacology, Sapienza University of Rome, 00185 Rome, Italy.

Francesca Grassi (F)

Department of Physiology and Pharmacology, Sapienza University of Rome, 00185 Rome, Italy.

Classifications MeSH