The Effect of Amino Acids on Production of SCFA and bCFA by Members of the Porcine Colonic Microbiota.

SCFA amino acids bCFA colon gut microbiota piglet

Journal

Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893

Informations de publication

Date de publication:
31 Mar 2022
Historique:
received: 24 01 2022
revised: 14 03 2022
accepted: 28 03 2022
entrez: 23 4 2022
pubmed: 24 4 2022
medline: 24 4 2022
Statut: epublish

Résumé

Functional amino acids supplementation to farm animals is considered to not only be beneficial by regulating intestinal barrier, oxidative stress, and immunity, but potentially also by impacting the gut microbiota. The impact of amino acids on a piglet-derived colonic microbiota was evaluated using a 48-h in vitro batch incubation strategy. The combination of 16S rRNA gene profiling with flow cytometry demonstrated that specific microbial taxa were involved in the fermentation of each of the amino acids resulting in the production of specific metabolites. Branched chain amino acids (leucine, isoleucine, valine) strongly increased branched-chain fatty acids (+23.0 mM) and valerate levels (+3.0 mM), coincided with a marked increase of

Identifiants

pubmed: 35456812
pii: microorganisms10040762
doi: 10.3390/microorganisms10040762
pmc: PMC9025589
pii:
doi:

Types de publication

Journal Article

Langues

eng

Références

Res Microbiol. 2013 May;164(4):288-92
pubmed: 23376087
FEMS Microbiol Ecol. 2004 Dec 27;51(1):143-53
pubmed: 16329863
Nutrients. 2020 Jun 29;12(7):
pubmed: 32610452
J Nutr. 2014 Jun;144(6):988-95
pubmed: 24670969
Appl Environ Microbiol. 2007 Aug;73(16):5261-7
pubmed: 17586664
Front Microbiol. 2018 Jul 31;9:1716
pubmed: 30108569
PLoS One. 2014 Apr 07;9(4):e94123
pubmed: 24709947
Amino Acids. 2014 Oct;46(10):2403-13
pubmed: 25023447
J Agric Food Chem. 2018 Feb 7;66(5):1121-1130
pubmed: 29363966
Nat Rev Gastroenterol Hepatol. 2017 Aug;14(8):491-502
pubmed: 28611480
Nature. 2017 Nov 23;551(7681):507-511
pubmed: 29143816
Nucleic Acids Res. 2009 Jan;37(Database issue):D141-5
pubmed: 19004872
Microbiome. 2019 Feb 19;7(1):28
pubmed: 30782206
Pharm Res. 1990 Nov;7(11):1163-6
pubmed: 2293216
Mol Nutr Food Res. 2012 Jan;56(1):184-96
pubmed: 22121108
Appl Environ Microbiol. 2013 Sep;79(17):5112-20
pubmed: 23793624
Gastroenterology. 2018 Nov;155(5):1495-1507.e15
pubmed: 30025704
J Nutr. 2013 Aug;143(8):1225-32
pubmed: 23761650
Gut Microbes. 2021 Jan-Dec;13(1):1987783
pubmed: 34693878
J Agric Food Chem. 2020 Nov 18;68(46):13102-13110
pubmed: 31909618
Front Microbiol. 2016 Jun 28;7:979
pubmed: 27446020
ISME J. 2017 Feb;11(2):584-587
pubmed: 27612291
Nutrients. 2020 Jul 29;12(8):
pubmed: 32751149
FEMS Microbiol Ecol. 2010 Dec;74(3):601-11
pubmed: 20946352
Appl Environ Microbiol. 2003 Mar;69(3):1511-20
pubmed: 12620837
Appl Environ Microbiol. 2011 May;77(10):3219-26
pubmed: 21421784
Front Microbiol. 2017 Sep 04;8:1688
pubmed: 28928724
Anaerobe. 2003 Aug;9(4):175-80
pubmed: 16887707
Appl Microbiol Biotechnol. 2001 Oct;57(3):263-73
pubmed: 11759672
Appl Environ Microbiol. 2006 Dec;72(12):7835-41
pubmed: 17056678
Microbiome. 2016 Jul 07;4(1):36
pubmed: 27388460
PLoS Comput Biol. 2017 Nov 3;13(11):e1005752
pubmed: 29099853
Poult Sci. 2019 Nov 1;98(11):5809-5819
pubmed: 31347673
Amino Acids. 2007 Nov;33(4):547-62
pubmed: 17146590
Vet Microbiol. 2010 Feb 24;141(1-2):73-80
pubmed: 19709819
Obes Facts. 2015;8(2):87-100
pubmed: 25791341
Nutr Rev. 2011 May;69(5):245-58
pubmed: 21521227
Environ Microbiol. 2017 Jan;19(1):29-41
pubmed: 27928878
Animals (Basel). 2020 Feb 19;10(2):
pubmed: 32092931
Eur J Clin Microbiol Infect Dis. 2020 Mar;39(3):403-413
pubmed: 31707507
Int J Syst Evol Microbiol. 2012 Jan;62(Pt 1):144-149
pubmed: 21357455
Pharm Res. 2014 Oct;31(10):2696-707
pubmed: 24792825
Nat Microbiol. 2019 Mar;4(3):396-403
pubmed: 30531975
Int J Syst Evol Microbiol. 2011 Aug;61(Pt 8):1875-1879
pubmed: 20833884
Korean J Anesthesiol. 2018 Oct;71(5):353-360
pubmed: 30157585
Amino Acids. 2016 Dec;48(12):2731-2745
pubmed: 27539648
Int J Pharm X. 2019 Jul 06;1:100021
pubmed: 31517286
J Nutr. 2002 May;132(5):1012-7
pubmed: 11983830
Front Vet Sci. 2021 May 25;8:663727
pubmed: 34113671
Amino Acids. 2022 Feb;54(2):157-168
pubmed: 35106634

Auteurs

Pieter Van den Abbeele (P)

ProDigest, 9052 Ghent, Belgium.
Cryptobiotix, 9052 Ghent, Belgium.

Jonas Ghyselinck (J)

ProDigest, 9052 Ghent, Belgium.

Massimo Marzorati (M)

ProDigest, 9052 Ghent, Belgium.
Center of Microbial Ecology and Technology (CMET), Ghent University, 9000 Ghent, Belgium.

Anna-Maria Koch (AM)

METEX NOOVISTAGO, 75017 Paris, France.

William Lambert (W)

METEX NOOVISTAGO, 75017 Paris, France.

Joris Michiels (J)

Laboratory for Animal Nutrition and Animal Product Quality, Ghent University, 9000 Ghent, Belgium.

Tristan Chalvon-Demersay (T)

METEX NOOVISTAGO, 75017 Paris, France.

Classifications MeSH