Primary nasopharyngeal amyloidosis with nasal polyposis: Case report of a diagnostic challenge.
Amyloidosis
Nasal
Nasopharyngeal
Polyposis
Journal
International journal of surgery case reports
ISSN: 2210-2612
Titre abrégé: Int J Surg Case Rep
Pays: Netherlands
ID NLM: 101529872
Informations de publication
Date de publication:
May 2022
May 2022
Historique:
received:
17
02
2022
revised:
01
04
2022
accepted:
05
04
2022
pubmed:
25
4
2022
medline:
25
4
2022
entrez:
24
4
2022
Statut:
ppublish
Résumé
Primary nasopharyngeal amyloidosis is a rare entity of localised amyloidosis. Patients usually present with symptoms that mimic other common nasal diseases. We report an unusual case of nasopharyngeal amyloidosis that co-exist with nasal polyposis at the same time. We described a 72-year-old gentleman who presented with left-sided nasal obstruction, rhinorrhoea and hyposmia and right-sided hearing loss. Examination revealed bilateral intranasal polyposis with right lobular swelling at torus tubarius and right sided middle ear effusion. Biopsy revealed inflammatory nasal polyps with nasopharyngeal amyloidosis. Patient was treated successfully with functional endoscopic sinus surgery (FESS) for nasal polyposis and an en bloc wide local excision of the torus tubarius with no signs of recurrence at one year follow-up. Clinicians should have raised index of suspicion of a possible primary nasopharyngeal amyloidosis in patients presenting with nasopharyngeal mass with co-existing nasal polyposis to avoid delay in diagnosis and treatment.
Sections du résumé
BACKGROUND
BACKGROUND
Primary nasopharyngeal amyloidosis is a rare entity of localised amyloidosis. Patients usually present with symptoms that mimic other common nasal diseases. We report an unusual case of nasopharyngeal amyloidosis that co-exist with nasal polyposis at the same time.
CASE PRESENTATION
METHODS
We described a 72-year-old gentleman who presented with left-sided nasal obstruction, rhinorrhoea and hyposmia and right-sided hearing loss. Examination revealed bilateral intranasal polyposis with right lobular swelling at torus tubarius and right sided middle ear effusion. Biopsy revealed inflammatory nasal polyps with nasopharyngeal amyloidosis. Patient was treated successfully with functional endoscopic sinus surgery (FESS) for nasal polyposis and an en bloc wide local excision of the torus tubarius with no signs of recurrence at one year follow-up.
CONCLUSION
CONCLUSIONS
Clinicians should have raised index of suspicion of a possible primary nasopharyngeal amyloidosis in patients presenting with nasopharyngeal mass with co-existing nasal polyposis to avoid delay in diagnosis and treatment.
Identifiants
pubmed: 35462145
pii: S2210-2612(22)00302-9
doi: 10.1016/j.ijscr.2022.107056
pmc: PMC9046795
pii:
doi:
Types de publication
Journal Article
Langues
eng
Pagination
107056Informations de copyright
Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.
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