Management of Primary Hyperparathyroidism.
Diagnosis
Epidemiology
Hyperparathyroidism
Medical management
Parathyroidectomy
Preoperative imaging
Primary
Journal
Indian journal of surgical oncology
ISSN: 0975-7651
Titre abrégé: Indian J Surg Oncol
Pays: India
ID NLM: 101532448
Informations de publication
Date de publication:
Mar 2022
Mar 2022
Historique:
received:
23
01
2021
accepted:
07
04
2021
entrez:
25
4
2022
pubmed:
26
4
2022
medline:
26
4
2022
Statut:
ppublish
Résumé
Primary hyperparathyroidism (PHPT) is the unregulated overproduction of parathyroid hormone (PTH) resulting in abnormal calcium homeostasis. The disease profile has evolved over the last century from symptomatic hyperparathyroidism to asymptomatic hyperparathyroidism. Primary hyperparathyroidism is a biochemical diagnosis. Parathyroidectomy is the only established cure for this disease. Every effort is made to localize the offending gland preoperaively with various imaging modalities. These localization studies along with intraoperative parathormone monitoring will direct the surgeon to either a focused parathyroidectomy or a four gland exploration. All symptomatic patients and asymptomatic patients who meet the criteria for surgery should undergo parathyroidectomy if no medical contraindications exist. Pharmacologic approaches are reserved for those patients unfit or unwilling to undergo surgery.
Identifiants
pubmed: 35462664
doi: 10.1007/s13193-021-01319-3
pii: 1319
pmc: PMC8986895
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
143-151Informations de copyright
© Indian Association of Surgical Oncology 2021.
Déclaration de conflit d'intérêts
Conflict of InterestThe author declares no competing interests.
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