Endothelial Dysfunction in Systemic Lupus Erythematosus and Systemic Sclerosis: A Common Trigger for Different Microvascular Diseases.
endothelial dysfunction
microvascular disease
systemic lupus erythematosus
systemic sclerosis
techniques of assessment
Journal
Frontiers in medicine
ISSN: 2296-858X
Titre abrégé: Front Med (Lausanne)
Pays: Switzerland
ID NLM: 101648047
Informations de publication
Date de publication:
2022
2022
Historique:
received:
05
01
2022
accepted:
04
03
2022
entrez:
25
4
2022
pubmed:
26
4
2022
medline:
26
4
2022
Statut:
epublish
Résumé
This review describes the complex interplay between inflammation, vasculopathy and fibrosis that involve the heart and peripheral small vessels, leading to endothelial stiffness, vascular damage, and early aging in patients with systemic lupus erythematosus and systemic sclerosis, which represents two different models of vascular dysfunction among systemic autoimmune diseases. In fact, despite the fact that diagnostic methods and therapies have been significantly improved in the last years, affected patients show an excess of cardiovascular mortality if compared with the general population. In addition, we provide a complete overview on the new techniques which are used for the evaluation of endothelial dysfunction in a preclinical phase, which could represent a new approach in the assessment of cardiovascular risk in these patients.
Identifiants
pubmed: 35462989
doi: 10.3389/fmed.2022.849086
pmc: PMC9023861
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
849086Informations de copyright
Copyright © 2022 Moschetti, Piantoni, Vizzardi, Sciatti, Riccardi, Franceschini and Cavazzana.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
PLoS One. 2015 Feb 06;10(2):e0114856
pubmed: 25658605
Microcirculation. 2019 Apr;26(3):e12440
pubmed: 29323451
PLoS One. 2017 Aug 10;12(8):e0183102
pubmed: 28797111
Exp Cell Res. 2008 Oct 1;314(16):2965-74
pubmed: 18692498
Clin Exp Immunol. 1989 Dec;78(3):359-65
pubmed: 2612050
Rev Recent Clin Trials. 2018;13(3):192-198
pubmed: 29542419
Ann Rheum Dis. 2015 Apr;74(4):778-85
pubmed: 24395554
RMD Open. 2019 Sep 20;5(2):e001012
pubmed: 31673412
Front Physiol. 2021 Oct 11;12:710298
pubmed: 34707506
Ann Transl Med. 2015 Jan;3(1):8
pubmed: 25705640
Clin Immunol. 2015 Oct;160(2):180-7
pubmed: 26148903
Ann Rheum Dis. 2017 Jan;76(1):17-28
pubmed: 27697765
Clin Immunol. 2021 Jan;222:108637
pubmed: 33232825
Autoimmun Rev. 2017 Mar;16(3):308-312
pubmed: 28147263
Lancet. 2004 Aug 14-20;364(9434):603-10
pubmed: 15313361
Nat Med. 2000 Oct;6(10):1183-6
pubmed: 11017152
Arthritis Rheum. 2006 Aug;54(8):2605-15
pubmed: 16868984
Science. 1997 Feb 14;275(5302):964-7
pubmed: 9020076
Lupus Sci Med. 2019 Oct 10;6(1):e000346
pubmed: 31749976
Arthritis Res Ther. 2016 Dec 30;18(1):306
pubmed: 28038677
Mayo Clin Proc. 2001 Oct;76(10):1011-20
pubmed: 11605685
Leukemia. 2007 Jun;21(6):1141-9
pubmed: 17392816
J Rheumatol. 2014 Apr;41(4):680-7
pubmed: 24532834
Rheumatology (Oxford). 2021 Jun 18;60(6):2834-2841
pubmed: 33383584
Ann Rheum Dis. 2009 Feb;68(2):191-5
pubmed: 18375538
Ann Rheum Dis. 2010 Oct;69(10):1809-15
pubmed: 20551155
Arthritis Res Ther. 2020 Nov 9;22(1):265
pubmed: 33168071
Eur Heart J Cardiovasc Imaging. 2014 Jul;15(7):736-46
pubmed: 24399339
N Engl J Med. 1990 Jul 5;323(1):22-7
pubmed: 2355955
Autoimmunity. 2001 May;33(3):171-9
pubmed: 11683377
Arthritis Rheum. 2005 Jul;52(7):2069-79
pubmed: 15986354
Ann Rheum Dis. 2022 Jun;81(6):768-779
pubmed: 35110331
Arthritis Rheum. 2007 Oct;56(10):3412-9
pubmed: 17907140
Lupus. 2005;14(7):521-5
pubmed: 16130507
Trends Cardiovasc Med. 2011 Oct;21(7):204-10
pubmed: 22867700
Arthritis Rheumatol. 2021 Feb;73(2):255-264
pubmed: 32783382
Arthritis Rheumatol. 2014 Jun;66(6):1568-73
pubmed: 24574329
J Rheumatol. 2000 Jan;27(1):155-60
pubmed: 10648032
Arthritis Rheumatol. 2014 Sep;66(9):2532-2544
pubmed: 24838349
Eur J Rheumatol. 2020 Oct;7(Suppl 3):S139-S146
pubmed: 31922471
Arthritis Rheum. 2001 Oct;44(10):2331-7
pubmed: 11665973
J Leukoc Biol. 2012 Oct;92(4):869-82
pubmed: 22822009
Int Immunopharmacol. 2020 Apr;81:106282
pubmed: 32066116
Arthritis Res Ther. 2019 Nov 27;21(1):253
pubmed: 31775852
Ann Rheum Dis. 2015 Jul;74(7):1441-9
pubmed: 24618261
Am J Med. 1976 Feb;60(2):221-5
pubmed: 1251849
Int J Mol Sci. 2019 Nov 07;20(22):
pubmed: 31703406
Nat Rev Rheumatol. 2015 Dec;11(12):693-704
pubmed: 26282082
Arterioscler Thromb Vasc Biol. 2017 Jul;37(7):1371-1379
pubmed: 28495931
Am J Cardiol. 1995 Feb 23;75(6):71B-74B
pubmed: 7863979
Arch Dermatol Res. 1995;287(5):439-42
pubmed: 7625853
Lab Invest. 2016 Jul;96(7):708-18
pubmed: 27183204
J Am Coll Cardiol. 2021 Apr 13;77(14):1717-1727
pubmed: 33832598
Lancet. 2017 Oct 7;390(10103):1685-1699
pubmed: 28413064
J Exp Med. 2012 Apr 9;209(4):819-35
pubmed: 22451716
PLoS One. 2017 Apr 17;12(4):e0174572
pubmed: 28414714
J Autoimmun. 2018 Aug;92:87-92
pubmed: 29859654
Sci Rep. 2017 Sep 7;7(1):10788
pubmed: 28883515
Semin Arthritis Rheum. 2019 Apr;48(5):867-873
pubmed: 30205980
Rheumatology (Oxford). 2021 Apr 6;60(4):1850-1857
pubmed: 33141226
Autoimmun Rev. 2017 Aug;16(8):787-795
pubmed: 28576600
Lancet. 1992 Nov 7;340(8828):1111-5
pubmed: 1359209
Mediators Inflamm. 2018 Dec 18;2018:3271572
pubmed: 30662367
Microvasc Res. 2017 May;111:20-24
pubmed: 27989404
Rheumatol Int. 2009 Dec;30(2):277-9
pubmed: 19701755
Arthritis Rheum. 1999 Jan;42(1):51-60
pubmed: 9920014
J Biomed Sci. 2014 Mar 17;21:23
pubmed: 24636579
Clin Exp Rheumatol. 2014 Nov-Dec;32(6 Suppl 86):S-133-7
pubmed: 24564981
Genet Mol Res. 2015 Nov 23;14(4):14871-81
pubmed: 26600548
Autoimmun Rev. 2021 Oct;20(10):102899
pubmed: 34274540
Front Immunol. 2018 Jun 18;9:1383
pubmed: 29967618
J Leukoc Biol. 2003 Nov;74(5):833-45
pubmed: 12960274
Clin Rheumatol. 2014 Aug;33(8):1099-104
pubmed: 24859783
Cell. 1994 Jan 28;76(2):301-14
pubmed: 7507411
Vascul Pharmacol. 2015 Aug;71:16-23
pubmed: 26044180
Rheumatol Int. 2021 Jun;41(6):1045-1053
pubmed: 33830321
Arthritis Rheumatol. 2015 May;67(8):2257-62
pubmed: 25891295
Arthritis Rheum. 2000 Nov;43(11):2550-62
pubmed: 11083280
Semin Arthritis Rheum. 2001 Jun;30(6):397-402
pubmed: 11404822
Adv Exp Med Biol. 2007;601:113-9
pubmed: 17712998
Postepy Dermatol Alergol. 2020 Oct;37(5):725-735
pubmed: 33240013
Arthritis Res Ther. 2012 Feb 20;14(1):203
pubmed: 22356717
Ann Rheum Dis. 2009 Feb;68(2):163-8
pubmed: 18653485
Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):893-900
pubmed: 17272749
J Rheumatol. 2011 Jul;38(7):1296-303
pubmed: 21459950
Sci Immunol. 2016 Dec 2;1(6):
pubmed: 28783690
Phys Med Biol. 2019 Mar 21;64(7):07TR01
pubmed: 30708364
J Cutan Pathol. 2004 Jan;31(1):43-50
pubmed: 14675284
Clin Exp Rheumatol. 2014 Nov-Dec;32(6 Suppl 86):S-154-60
pubmed: 25372799
Lupus. 2016 Jun;25(7):727-34
pubmed: 26811368
Clin Chim Acta. 2014 Jan 1;427:6-10
pubmed: 24076252
Ann Rheum Dis. 2012 Mar;71(3):408-14
pubmed: 21953346
J Hypertens. 2021 May 1;39(5):867-868
pubmed: 33824257
Circ J. 2012;76(9):2273-9
pubmed: 22664650
J Immunol. 2016 Mar 1;196(5):2063-74
pubmed: 26829984
Clin Rheumatol. 2021 Dec;40(12):4957-4968
pubmed: 34312764
Mediators Inflamm. 2016;2016:2842143
pubmed: 27065298
J Rheumatol. 2015 Feb;42(2):222-7
pubmed: 25399393
Nature. 2021 Apr;592(7855):524-533
pubmed: 33883728
J Leukoc Biol. 2016 Mar;99(3):405-12
pubmed: 26232454
Arthritis Res Ther. 2021 Jun 27;23(1):175
pubmed: 34176504
Semin Arthritis Rheum. 2003 Apr;32(5):285-95
pubmed: 12701039
Rheumatology (Oxford). 2001 Oct;40(10):1089-96
pubmed: 11600736
Blood. 2007 Oct 15;110(8):2907-15
pubmed: 17638846
Front Physiol. 2017 Aug 23;8:600
pubmed: 28878685
Arthritis Rheum. 2009 Aug;60(8):2480-9
pubmed: 19644882
Trends Pharmacol Sci. 2013 Jul;34(7):373-84
pubmed: 23791036
Rheumatol Int. 2017 Jan;37(1):85-95
pubmed: 27405985
Front Immunol. 2018 Nov 02;9:2457
pubmed: 30464761
Front Immunol. 2020 Nov 11;11:581385
pubmed: 33262760
Eur Heart J. 2010 May;31(9):1142-8
pubmed: 20181680
Ann Rheum Dis. 2015 Jul;74(7):1417-24
pubmed: 24570026
J Hypertens. 2017 May;35(5):914-921
pubmed: 28355167
J Cutan Pathol. 2007 Feb;34(2):146-53
pubmed: 17244026
Circulation. 2007 Oct 9;116(15):1671-82
pubmed: 17909106
Am Heart J. 2003 Jul;146(1):168-74
pubmed: 12851627
Eur J Dermatol. 2015 Sep-Oct;25(5):444-51
pubmed: 26693634
Intervirology. 2009;52(5):279-82
pubmed: 19672101
Arthritis Rheum. 1973 Sep-Oct;16(5):619-28
pubmed: 4742842
Clin Chim Acta. 2015 Feb 20;441:33-43
pubmed: 25512166
Circulation. 2004 Jun 8;109(22):2744-8
pubmed: 15159291
Heart. 2004 Aug;90(8):859-65
pubmed: 15253953
Nat Rev Rheumatol. 2010 Jul;6(7):430-4
pubmed: 20517296
Arthritis Res Ther. 2015 Mar 07;17:47
pubmed: 25890027
Rheumatology (Oxford). 2010 Sep;49(9):1776-82
pubmed: 20538680
Circulation. 2000 Jun 27;101(25):2883-8
pubmed: 10869258
Autoimmun Rev. 2017 Aug;16(8):774-786
pubmed: 28572048
Clin Immunol Immunopathol. 1992 Apr;63(1):39-44
pubmed: 1591881
Biomed Res Int. 2014;2014:178721
pubmed: 24790989
Science. 2015 Jul 17;349(6245):316-20
pubmed: 26185250
Eur J Prev Cardiol. 2022 Feb 19;29(1):5-115
pubmed: 34558602
J Dermatol. 2020 Jun;47(6):609-614
pubmed: 32232898
Lupus. 2019 Feb;28(2):210-216
pubmed: 30608206
Int J Cardiol. 2009 May 1;134(1):52-8
pubmed: 18479768
Curr Opin Rheumatol. 2021 Mar 1;33(2):211-218
pubmed: 33394753
Acta Reumatol Port. 2009 Apr-Jun;34(2A):219-27
pubmed: 19474777
Arthritis Res Ther. 2011 Aug 26;13(4):237
pubmed: 21888685
N Engl J Med. 2009 May 7;360(19):1989-2003
pubmed: 19420368
Front Immunol. 2020 Oct 29;11:572876
pubmed: 33193356
J Intern Med. 2015 Nov;278(5):494-506
pubmed: 25720452
Arthritis Rheumatol. 2016 Jan;68(1):210-7
pubmed: 26360820
Hypertension. 2001 Aug;38(2):238-42
pubmed: 11509483
Arthritis Rheum. 2013 Aug;65(8):1953-62
pubmed: 23666787
Rheumatology (Oxford). 2012 Jun;51(6):1042-8
pubmed: 22271757
Arthritis Res Ther. 2013 Jul 11;15(4):R74
pubmed: 23845159
Clin Rheumatol. 2021 Jun;40(6):2457-2465
pubmed: 32959188
Immunity. 2016 May 17;44(5):1034-51
pubmed: 27192568
Arthritis Rheum. 2012 Sep;64(9):2975-85
pubmed: 22549550
J Clin Invest. 1993 Oct;92(4):1866-74
pubmed: 7691889
Chest. 2001 Sep;120(3):796-800
pubmed: 11555512
Rheumatol Ther. 2021 Mar;8(1):81-94
pubmed: 33420626
Circulation. 2012 Aug 7;126(6):753-67
pubmed: 22869857
J Rheumatol. 2016 May;43(5):875-9
pubmed: 26879352
Clin Exp Rheumatol. 2015 Jul-Aug;33(4 Suppl 91):S92-7
pubmed: 25797836
Stroke. 2012 Jan;43(1):256-8
pubmed: 21980212
Clin Rheumatol. 2019 Sep;38(9):2613-2620
pubmed: 31030360
Lupus. 2014 Oct;23(12):1302-4
pubmed: 25228733
Int J Mol Sci. 2019 Aug 09;20(16):
pubmed: 31395799
Ann Rheum Dis. 2007 Jul;66(7):940-4
pubmed: 17329309
Autoimmun Rev. 2016 Jan;15(1):22-37
pubmed: 26455562
Arthritis Rheum. 2007 Nov;56(11):3759-69
pubmed: 17968925
PLoS One. 2017 Mar 30;12(3):e0174703
pubmed: 28358906
Immunol Lett. 2018 Mar;195:83-87
pubmed: 29032187
Free Radic Biol Med. 2013 Jul;60:80-8
pubmed: 23385031
J Leukoc Biol. 2006 Mar;79(3):555-63
pubmed: 16415174
Int J Cardiol. 2011 Sep 15;151(3):342-7
pubmed: 20832878
Arthritis Rheum. 2000 May;43(5):1085-93
pubmed: 10817563
Br J Dermatol. 2008 Jan;158(1):141-4
pubmed: 18028496
Ann Rheum Dis. 2013 Nov;72(11):1747-55
pubmed: 24092682
Curr Rheumatol Rev. 2019;15(3):177-188
pubmed: 30474532
Basic Clin Pharmacol Toxicol. 2010 Dec;107(6):919-24
pubmed: 20560926
Lupus. 2015 Mar;24(3):227-30
pubmed: 25631854
J Rheumatol. 2020 Nov 1;47(11):1652-1660
pubmed: 31839592
J Hypertens. 2021 May 1;39(5):970-978
pubmed: 33196557
Nat Rev Rheumatol. 2011 Jun;7(6):330-9
pubmed: 21556027
Ann Rheum Dis. 2015 May;74(5):921-7
pubmed: 24399233
Circulation. 2012 Apr 3;125(13):1673-83
pubmed: 22388324
Arthritis Care Res (Hoboken). 2018 Sep;70(9):1277-1283
pubmed: 29245186
J Thromb Haemost. 2015 Oct;13(10):1928-40
pubmed: 26264622
Arthritis Care Res (Hoboken). 2017 Jun;69(6):849-856
pubmed: 28129475
Circulation. 2007 May 8;115(18):2390-7
pubmed: 17452608
J Clin Rheumatol. 2006 Dec;12(6):324-6
pubmed: 17149072
Lupus. 2016 Apr;25(5):525-31
pubmed: 26678442
Rheumatology (Oxford). 2013 Aug;52(8):1525-8
pubmed: 23671125