Pituitary apoplexy following adenoviral vector-based COVID-19 vaccination.
COVID-19 Vaccine AstraZeneca
COVID-19, Coronavirus disease 2019
Coronavirus disease 2019 (COVID-19)
MRI, Magnetic resonance imaging
Magnetic resonance imaging (MRI)
Menstrual changes
PA, Pituitary apoplexy
Pituitary apoplexy
VITT, Vaccine-induced immune thrombotic thrombocytopenia
Vaxzevria®
Journal
Brain hemorrhages
ISSN: 2589-238X
Titre abrégé: Brain Hemorrhages
Pays: Netherlands
ID NLM: 101763734
Informations de publication
Date de publication:
Mar 2023
Mar 2023
Historique:
received:
26
03
2022
revised:
09
04
2022
accepted:
13
04
2022
pubmed:
26
4
2022
medline:
26
4
2022
entrez:
25
4
2022
Statut:
ppublish
Résumé
Pituitary apoplexy (PA) may complicate the course of coronavirus disease 2019 (COVID-19), posing a potential threat to life. Among vaccines designed to prevent COVID-19, there are those adenoviral vector-based, such as Vaxzevria® (formerly COVID-19 Vaccine AstraZeneca). The product insert states that it can cause very rare coagulation disorders, in particular thrombosis with thrombocytopenia syndrome in some cases accompanied by bleeding, cerebrovascular venous or sinus thrombosis, and thrombocytopenia, including immune thrombocytopenia, also associated with bleeding. Here, we report the onset of PA after Vaxzevria® in a 28-year-old healthy Caucasian female, who experienced long-lasting tension-type headache, hyperprolactinemia and menstrual changes, without thrombocytopenia or thrombosis.
Identifiants
pubmed: 35464129
doi: 10.1016/j.hest.2022.04.002
pii: S2589-238X(22)00015-8
pmc: PMC9017089
doi:
Types de publication
Journal Article
Langues
eng
Pagination
27-29Informations de copyright
© 2022 International Hemorrhagic Stroke Association. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.
Déclaration de conflit d'intérêts
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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